Dr. Haiyan Liu

Dr. Haiyan LiuHAIYAN LIU, MD
Anatomic Pathology, Clinical Pathology, Cytopathology
Director, Cytopathology Fellowship Program


100 North Academy Avenue
Danville, PA 17822-1920
1 800 695 6491

Dr. Liu is an Associate of Geisinger Medical Laboratories at Geisinger Medical Center in Danville Pennsylvania. She is also the Director of the Cytopathology Fellowship Program.

Education:

She received her MD from Wenzhou Medical College, Zhejiang, P.R. China, in 1983. Dr. Liu completed residency training in OB/GYN and Wenzhou Medical College and fellowship training in the Practical Use of Laparoscope at Shanghai Second Medical School - Xinhua Hospital Department of OB-GYN. She also completed fellowship training in OB/GYN at Beijing OB/GYN Hospital, Beijing, P. R. China. Dr. Liu completed her pathology residency at the Penn State/Milton S. Hershey Medical Center in Hershey, Pennsylvania, and cytopathology fellowship training at Geisinger Medical Center in Danville.

Certifications:

Dr. Liu is board-certified in both anatomic and clinical pathology as well as cytopathology. She specializes in cytopathology, gastrointestinal pathology, thyroid pathology and genitourinary .

Professional Affiliations:

The United States and Canadian Academy of Pathology (USCAP)
American Society of Cytopathology (ASCP)
College of American Pathologists (CAP)
Pennsylvania Association of Pathologists
Pennsylvania Medical Society

Research Interests:

Her research interests include renal pathology.

Publications in Peer-Reviewed Journals:

Nelson R, Fellowes V, Jin P, Liu Hui, Highfill S, Ren J, Szymanski J, Flegel W, Stroncek, D. Group O Plasma as a Media Supplement for CAR-T Cells and other Adoptive T-Cell Therapies. Transfusion.2020; 60(5):1004-1014.

Lin F, Shi J, Bitting A, Lin B, Liu H. Impact of Decalcification Time and Formalin Fixation Time on Immunohistochemical Detection of PD-L1 Expression in Cultured Carcinoma Cell Lines. Arch Pathol Lab Med.2019; In:Press.

Liu H, Lin F. NKX3.1: A novel marker for prostatic adenocarcinoma. Arch Pathol Lab Med.2019; In:Prep.

Zhang B, Shi J, Liu H, Monroe R, Lin F. Utility of HPV E6 and E7 mRNA in situ Hybridization in Diagnosing Cervical Low-Grade Squamous Intraepithelial Lesion. Am J Clin Pathol.2019; In:Prep.

Sarami I, Shi J, Lin B, Liu H, Monroe R, Lin F. Evaluation of Human Kidney Injury Molecule-1 (hKIM-1) Expression in Tumors from Various Organs by mRNA in situ Hybridization. Mod Pathol.2019; In:Prep.

Liu H, Ljungren C, Lin F, Zarka MA, and Chen L. Analysis of Histologic Follow-up and Risk of Malignancy for Salivary Gland Neoplasm of Uncertain Malignant Potential Proposed by the Milan System for Reporting Salivary Gland Cytopathology. Cancer Cytopathol.2018; 126(7):490-497.

Liu H, Shi J, Lin F. The potential diagnostic utility of TROP-2 in thyroid neoplasms. Appl Immunohistochem Mol Morphol.2017; 25(8):525-533.

Liu H, Shi J, Ma X, Lin F, et al. RNA in situ hybridization is a more sensitive method than immunohistochemistry in detection of GCDFP15 in breast carcinomas. Am J Clin Pathol.2017; In :preparation.

Kandukuri SR, Lin F, Gui L, Gong Y, Fan F, Chen L, Cai G, Liu H. Application of Immunohistochemistry in Undifferentiated Neoplasms: A Practical Approach. Arch Pathol Lab Med.2017; 141(8):1014-1032.

Abstracts, Posters, and Other Presentations:

Mohammad M, Shi J, Liu H, Lin F. Immunohistochemical evaluation of insulinoma-associated protein 1 (INSM1) expression on tumors and normal tissues from various organs. Abstract United States and Canadian Academy of Pathology , Los Angeles, California, February 29-March 5, 2020.

Absar F, Shi J, Liu H, Lin F. Immunohistochemical evaluation of loss of expression of BRCA-1 associated protein 1 (BAP1) on tumors and normal tissues from various organs. Abstract United States and Canadian Academy of Pathology , Los Angeles, California, February 29-March 5, 2020.

Zelonis M, Shi J, Liu H, Monroe R, Lin F. Detection of cervical squamous dysplasia on cell blocks prepared from Pap test samples - A combined study based on morphology, HPV detection by RNA in situ hybridization, and immunohistochemical stains for p16 and Ki-67. Abstract United States and Canadian Academy of Pathology , Los Angeles, California, February 29-March 5, 2020.

Tabish N, SHi J, Liu H, Lin F. Immunohistochemical evaluation of nuclear protein in testis (NUT) expression on tumors and normal tissues from various organs. . Abstract United States and Canadian Academy of Pathology , Los Angeles, California, February 29-March 5, 2020.

Mohammad M, Shi J, Li A, Liu H, Lin F. Immunohistochemical evaluation of orthopedia homeobox (OTP) expression on tumors and normal tissues from various organs. Abstract United States and Canadian Academy of Pathology , Los Angeles, California, February 29-March 5, 2020.

Kim P, Lin F, Shi J, Bitting A, Liu H. Use of Immunohistochemistry to Distinguish Normal Gastric and Duodenal Mucosa from Intraductal Papillary Mucinous Neoplasms. Abstract United States and Canadian Academy of Pathology , Los Angeles, California, February 29-March 5, 2020.

Lin F, SHi J, Chen , Yin H, Monroe R, Liu H. Detection of Anaplastic Lymphoma Kinase (ALK) Gene Rearrangement by RNA in situ Hybridization in Lung Adenocarcinomas. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Zhang B, Lin F, Frank R, Liu H. The reduction of atypia of undetermined significance (AUS)/follicular lesion of undetermined significance (FLUS) rate by quality assurance measures and their financial impact. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Sarami I, Shi J, Lin B, Liu H, Monroe R, Lin F. Evaluation of Human Kidney Injury Molecule-1 (hKIM-1) Expression in Tumors from Various Organs by mRNA in situ Hybridization. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Lin B, Zelonis M, Lin F, Liu H. Accuracy between ThyroSeq v2 and ThyroSeq v3 Molecular Test for Indeterminate Thyroid Nodules. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Liu H, Shi J, Monroe R, Lin F. Utility of T RO P-2 by RNA in situ Hybridization in Diagnosing Papillary Thyroid Carcinomas. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, National Harbor, Maryland, March 16-21, 2019.

Liu H, Bitting A, Lin D, Lin F. Immunohistochemical Detection of PD-L1 Expression on Bladder Small Cell Carcinomas Using Ventana SP263 Clone. Presentation College of American Pathologists, Orlando, Floria, October 20-24-2018.

Lin F, Shi J, Lin B, Li A, Liu H. Immunohistochemical Detection of EGFR L858R Mutation in Lung Adenocarcinomas Using a Point Mutation Specific Monoclonal Antibody. Presentation College of American Pathologists, Orland, Floria, October 20-24-2018.

Rosengrant AJ, Lin F, Liu H. The Analysis and Diagnostic Correlation of NIFTP with Previous Thyroid Fine Needle Aspiration Specimens. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, Vancouver, British Columbia, March 17-23, 2018.

Borodin VS, Lin F, Liu H. Immunohistochemical Evaluation of PAX-8 Expression in Various Benign Fluid Specimens. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, Vancouver, British Columbia, March 17-23, 2018.

Liu H, Shi J, Lin D, Li A, Lin F. Immunohistochemical Evaluation of PAX-6 in Neuroendocrine and Non-neuroendocrine Tumors from Various Organs. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, Vancouver, British Columbia, March 17-23, 2018.

Lin F, Shi J, Bitting A, Lin B, Liu H. Impact of Decalcification Time on Immunohistochemical Detection of PD-L1 Expression in Cultured Carcinoma Cell Lines. Presentation United States and Canadian Academy of Pathology (USCAP) Meeting, Vancouver, British Columbia, March 17-23, 2018.

Liu H, Shi J, Lin F. . Immunohistochemical detection of VHL expression is more sensitive than detection of albumin mRNA in the diagnosis of intrahepatic cholangiocarcinomas on fine needle aspiration and small tissue biopsy specimens. Presentation American Society of Cytopathology, Phoenix, Arizona, November 10-17, 2017.

Lin F, Bitting A, Liu H. Immunohistochemical profiles of normal testicular adnexal structures – rete testis, epididymis and vas deferens. Presentation College of American Pathologists, Oxon Hill, Maryland, October 8-11, 2107.

Lin F, Bitting A, Chen Z, Liu H. Immunohistochemical Evaluation and Comparison of Expression of Three Thyroid Transcription Factor 1 (TTF1) Clones in Neoplasms and Normal Tissues. Presentation College of American Pathologists, Oxon Hill, Maryland, October 8-11, 2107.

Liu H, SHi J, Lin F. The Validation and Utility of Immunoassay for CK 8/18 on Frozen Tissue Section. Presentation College of American Pathologists, Oxon Hill, Maryland, October 8-11, 2107.

Piazza Y, Liu H, Lin F. Immunohistochemical Detection of Loss Expression of ATRX/DAXX in Neuroendocrine Tumors from Various Organs. Poster presentation United States and Canadian Academy of Pathology, San Antonio, Texas, March 4-10, 2017.

Swarrow RS, Liu H, Lin F. Diagnostic Utility of VHL, Maspin, IMP3 and S100P in the Evaluation of Pancreatic Resection Margins from Frozen Tissue. Poster presentation United States and Canadian Academy of Pathology, San Antonio, Texas, March 4-10, 2017.

Piazza Y, Lin F, Liu H. The Correlation of Afirma® Gene Expression Classifier Results with Follow-Up Findings for Thyroid Fine Needle Aspiration Specimens. Poster presentation United States and Canadian Academy of Pathology, San Antonio, Texas, March 4-10, 2017.

Swarrow RS, Lin F, Liu H. Analysis of the atypia of undetermined significance/follicular lesion of undetermined significant (AUS/FLUS) category – experience from a large health system. Poster presentation United States and Canadian Academy of Pathology, San Antonio, Texas, March 4-10, 2017.

Liu H, Wilkerson M, Lin F. NKX3.1 is the Most Sensitive Immunohistochemical Marker in Identifying Metastatic Prostatic Carcinomas. Poster presentation United States and Canadian Academy of Pathology, San Antonio, Texas, March 4-10, 2017.

Liu H, Wilkerson M, Lin F. Immunohistochemical Evaluation of NKX3.1 Expression in Prostatic Ductal Adenocarcinomas. Poster presentation United States and Canadian Academy of Pathology, San Antonio, Texas, March 4-10, 2017.

Textbook Chapters

Liu H, Wilkerson M, Lin F. Thyroid, parathyroid and adrenal glands. In Lin F, Prichard J, Liu H, Wilkerson M, eds. Handbook of Practical Immunohistochemistry: Frequently Asked Questions, 3rd ed.. Springer, New York, New York, 2020, In press.

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