Dr. Julie W. Hirschhorn

Dr. Julie HirschhornJulie W. Hirschhorn, PhD, HCLD (ABB)
System Director, Molecular Microbiology

100 North Academy Avenue
Danville, PA  17822-1920

Dr. Hirschhorn is an associate at Geisinger Medical Center in Danville, Pennsylvania, where she serves as the system director of Molecular Microbiology.




Dr. Hirschhorn received her PhD in cancer biology and post-doctoral training in cancer biology and translational research at the Medical University of South Carolina.


Dr. Hirschhorn is board-certified by the American Board of Bioanalysis (ABB) as a high-complexity laboratory director and as a technical supervisor in molecular diagnostics.

Professional Affiliations:

American Society of Microbiology
Association of Molecular Pathology
Clinical and Laboratories Standards Institute

Research Interests:

Molecular microbiology, microbiology, PCR, next-generation sequencing, and bioinformatics.

Recent Academic Activity

Publications in Peer-Reviewed Journals:

Hirschhorn JW, Dunne J. SARS-CoV-2 Sequencing for Variant Surveillance. Methods Mol Biol. 2023;2621:279-292.

Hirschhorn JW, Avery A, Schandl CA. Managing a PCR Contamination Event in a Molecular Pathology Laboratory. Methods Mol Biol. 2023;2621:15-26.

Rodgers MA, Olivo A, Harris BJ, Lark C, Luo X, Berg MG, Meyer TV, Mohaimani A, Orf GS, Goldstein Y, Fox AS, Hirschhorn J, Glen WB, Nolte F, Landay A, Jennings C, Moy J, Servellita V, Chiu C, Batra R, Snell LB, Nebbia G, Douthwaite S, Tanuri A, Singh L, de Oliveira T, Ahouidi A, Mboup S, Cloherty GA. Detection of SARS-CoV-2 variants by Abbott molecular, antigen, and serological tests. J Clin Virol. 2022; 147:105080.

Carter AB, Abruzzo LV, Hirschhorn JW, Jones D, Jordan DC, Nassiri M, Ogino S, Patel NR, Suciu CG, Temple-Smolkin RL, Zehir A, Roy S. Electronic Health Records and Genomics: Perspectives from the Association for Molecular Pathology Electronic Health Record (EHR) Interoperability for Clinical Genomics Data Working Group. J Mol Diagn. 2022;24(1):1-17.

Babic N, Garner KS, Hirschhorn JW, Zebian R, Nolte FS. Evaluation of Abbott ID NOW COVID-19 POC test performance characteristics and integration in the regional health network workflows to improve health care delivery. Clin Biochem. 2021;8:S0009-9120(21)00320-9.

Hirschhorn JW, Kegl A, Dickerson T, Glen WB Jr, Xu G, Alden J, Nolte FS. Verification and Validation of SARS-CoV-2 Assay Performance on the Abbott m2000 and Alinity m Systems. J Clin Microbiol. 2021;59(5):e03119-20.

Hirschhorn JW, Snider JS, Lindsey KG, Schandl CA. Molecular profiling of vitreous fluid by massively parallel sequencing: a case series. J Am Soc Cytopathol. 2020;9(4):254-257.

Snider JS, Hirschhorn JW, Yang J, Chajewski OS, Houston PM, Lindsey KG. Three-year review of gene sequencing analyses of pulmonary non-small cell lung cancers obtained by fine-needle aspiration or surgical biopsy: mutation and failure rates. J Am Soc Cytopathol. 2018;7(6):300-305.

Other Publications:

Case Reports Surgical Pathology 2020 Exercise 5: The Histopathologic Classification and Diagnostic Considerations of Thymomas, American Society for Clinical Pathology 12 (2020). This is an online activity in surgical pathology that offers 2.0 continuing education (CME/SAM/) credit that can be used to fulfill CC Part II and CMP requirements.

Abstracts, Posters, and Other Presentations:

Kegl, A., Sasaki, M., Akter, T., Dickerson, T., Lucic, D., & Hirschhorn, J. W. (2022, September). Performance Evaluation of the high-throughput quantitative Alinity m EBV assay. In Pan American Society for Clinical Virology. Pan American Society for Clinical Virology.

Kegl, A., Sasaki, M., Akter, T., Dickerson, T., Lucic, D., & Hirschhorn, J. W. (2022, September). Performance Evaluation of the high-throughput quantitative Alinity m CMV assay. In Pan American Society for Clinical Virology. Pan American Society for Clinical Virology.

Hirschhorn, J. W., Glen, W. B., & Kirchoff, K. (2022). COVID-19 Variant Surveillance Database and Integration into MUSC Research Data Warehouse. In 2022 MUSC Innovation Week. Medical University of South Carolina.

Hirschhorn, J. W. (2022). NGS-Based Testing for Oncology: Overview and Update. Southeast Regional Genetics Conference. The Foundation for Genetic Technology. Charleston, SC.

Hirschhorn, J. W. (2022). Learn, Prepare, and Find the Path Forward. In COVID-19 Pandemic: Moving Forward. Public Information & Community Outreach, Department of Energy Community Leaders Institute, and Allen University.

Hirschhorn, J. W. (2022). COVID-19 Update. In Lowcountry COVID-19 Epidemiologist Team Meeting. SC Department of Health and Environmental Control.

Hirschhorn, J. W., Snider, J., & Schandl, C. A. (2019). Mutation Profiling by Next Generation Sequencing in Low-Yield DNA Intraocular Liquid Biopsies: A Case Series. In Association of Molecular Pathology Annual Meeting. Association of Molecular Pathology.

Hirschhorn, J. W., & Schandl, C. A. (2019). Finding flexibility in a resource limited world: Considerations for amplicon-based NGS enrichment in laboratories running multiple sample and assay types. In Corporate Workshop, Association of Molecular Pathology Annual Meeting. Pillar Biosciences.

Emanuael, A., Jester, R., Chajewski, O. S., Yang, J., Schandl, C. A., Hirschhorn, J. W., & Lindsey, K. G. (2019). Single Smear Total Nucleic Acid Extraction: Shooting FISH in a Barrel. In United States and Canadian Academy of Pathology (USCAP) Annual Meeting. United States and Canadian Academy of Pathology. Pathology Resident abstract submitted and chosen for a platform presentation

Textbook Chapters

Hirschhorn, J. W., Schandl, C. A., & Nolte, F. S. (2021). Polymerase Chain Reaction and other Nucleic Acid Amplification Technology. In Henry’s Clinical Diagnosis and Management by Laboratory Methods, 24/e (No. 24). Elsevier Inc.


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