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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
THYROID PEROXIDASE ANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB3160 Geisinger Epic ID: 19785 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
Gold-top (serum separator) microcollection tube
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
One (1) full 3.5 mL gold-top serum separator tube. Aliquot also acceptable (0.5 mL minimum). | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow serum to clot. Centrifuge to separate serum within 2 hours of collection. | |
Transport temperature: |
Refrigerated (preferred) or frozen. | |
Specimen stability: |
Refrigerated: 3 days. Frozen: 1 month. | |
Rejection criteria: |
Stability limit exceeded. | |
TEST DETAILS |
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Reference interval: |
Less than 34 IU/mL. | |
CPT code(s): |
86376 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Thyroid peroxidase antibody value. | |
Synonyms: |
TPAB, Thyroid Microsomal Antibody Thyroid peroxidase antibody Antimicrosomal antibodies TPO autoantibody Antithyroperoxidase Thyroperoxidase antibody
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Clinical significance: |
The major thyroid autoimmune diseases are Hashimoto's thyroiditis and Graves' disease. In virtually all cases of Hashimoto's disease and in the majority of cases of Graves' disease cases, TPO autoantibodies are elevated. High levels of TPO autoantibodies in the context of hypothyroidism confirm the diagnosis of Hashimoto's disease. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu, PhD, DABCC Sheng-Ying (Margaret) Lo, PhD, DABCC |
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| Review Date: | 12/14/2022 | |