Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

FACTOR II (2) CLOTTING ACTIVITY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2251         Geisinger Epic ID: 7120

SPECIMEN COLLECTION
Specimen type:
Platelet-free plasma
Preferred collection container:
Alternate Collection Container:
Other size blue-top (3.2% sodium citrate) tubes (e.g., 1.8 mL, 4.5 mL)
Specimen required:
1 mL aliquot plasma.
Special notes:
Do not draw blood from a heparinized line. Avoid contaminating the sample with tissue thromboplastin or heparin. Venipuncture must be performed with no trauma. If blood is drawn from an indwelling catheter, flush with 5 mL of saline and discard the first 5 mL of blood collected.

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge the citrated blue-top tubes as soon as possible (within 60 minutes) at designated time and speed to obtain platelet-poor plasma (<10,000/µL). Using a plastic pipette, remove 1 mL of plasma and transfer to a plastic polypropylene aliquot tube and label with patient's name and a second aliquot tube and label with patient's name and a second patient identifier (e.g., date of birth, medical record number). Freeze upright and transport on dry ice. 
Transport temperature:
Frozen.
Specimen stability:
Frozen: -20°C for 30 days, -70°C for 6 months. Room temperature: 4 hours.
Rejection criteria:
Clotted specimen. Stability limits exceeded. Indications of thaw in transit are sample on slant in aliquot tube or in lid of tube. These samples will be run but will receive a comment of interpret results with caution as thawing suspected.

TEST DETAILS
Reference interval:
83-117%.
Additional information:
Anticoagulation Impact on Coagulation Tests
CPT code(s):
85210
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Factor II activity.
Methodology:
Mechanical Clot-Based
Synonyms:
FA2, Factor 2, Factor II
Clinical significance:
Factor 2 (aka prothrombin) is a blood protein involved in blood clot formation. It is made in the liver and requires vitamin K for its synthesis. Low levels are can result in a bleeding disorder. Factor 2 levels are decreased in patients with congenital deficiencies (rare), acquired factor 2 antibodies (rare), vitamin K antagonist (warfarin), vitamin K deficiency from poor oral intake, malabsorption, or improper metabolism (hemorrhagic disease of newborn, cholestasis, certain antibiotic therapy), liver disease, and DIC. Testing is utilized in bleeding patients that have both a prolonged PT and APTT.
Doctoral Director(s:)
Michelle Grant DO    
Review Date: 01/03/2021

Performing Locations

Geisinger Medical Center

Performing laboratory: Coagulation
Technical Lead: Margaret Knowles-Tuchman
Frequency: Daily, 1st shift
Performed stat? No
Locations  |    Search  |    Site Map |   Contact Us
©2000-2021 Geisinger Health System.   All rights reserved.