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Geisinger Medical Laboratories Test Catalog
BNP, NT-PRO |
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Geisinger Epic Procedure Code: LAB1873
Geisinger Epic ID: 21325
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SPECIMEN COLLECTION |
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Specimen type: |
Plasma or serum | |
Preferred collection container: |
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Specimen required: |
2 mL aliquot serum or plasma; minimum 0.5 mL. | |
Special notes: |
PLASMA FROM EDTA LAVENDER-TOP TUBES CANNOT BE USED. | |
Patient preparation: |
If patient is receiving biotin, no sample is to be taken until at least 8 hours after last biotin administration. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow serum to clot. Centrifuge to separate serum or plasma within 2 hours of collection. | |
Transport temperature: |
Room temperature (preferred). | |
Specimen stability: |
Room temperature: 3 days. Refrigerated: 6 days. Frozen: 24 months. | |
Rejection criteria: |
Stability limits exceeded. | |
TEST DETAILS |
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Interpretation guide: |
Adults: Exclude Heart Failure: <300 pg/mL Diagnose Heart Failure: Age <50 yr: >450 pg/mL 50-75 yr: >900 pg/mL >75 yr: >1800 pg/mL *GFR is 30-59 mL/min: > 1200 pg/mL or age-adjusted values GFR < 30 mL/min: do not use, not reliable Prognostic threshold: 1000 pg/mL Children: NT-ProBNP (as well as BNP) values are generally very high at birth and rapidly fall within the first few weeks. Pediatric reference intervals below are based on Nir et al Pediatr Cardiol (2009, 30:3-8) and other studies. 0-2 days: 321-13222 pg/mL 3-11 days: 263 -6502 pg/mL >1 mo to 1 year: 37-1000 pg/mL >1 to 2 years: 39-675 pg/mL >2 to 6 years: 23-327 pg/mL |
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CPT code(s): |
83880 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Electrochemiluminescence Immunoassay |
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Synonyms: |
proBNP PRO BNP; BNPNTPRO; BNP-NTPRO; NTPROBNP; NT-PROBNP PRO BRAIN NATRIURETIC PEPTIDE
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Clinical significance: |
N terminal pro B-type natriuretic peptide (NTproBNP) is a split product of proBNP that correlates with release of this hormone during left vetricular dysfunction and heart failure. NTproBNP does not suffer interference from exogenous BNP used to treat congestive heart failure. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu, PhD, DABCC, FADLM Sheng-Ying (Margaret) Lo, PhD, DABCC |
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| Review Date: | 12/14/2022 | |
Performing Locations
Geisinger Wyoming Valley Medical Center
Geisinger Shamokin Area Community Hospital
Geisinger Community Medical Center
Geisinger Medical Center Muncy