Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Test Name: Sunquest Test Code Epic Procedure Code Or ID CPT Code:  

PROLACTIN

ORDERING INFORMATION:
Sunquest Test Code:
PROL      Geisinger Epic Procedure Code: 84146         Geisinger Epic ID: 6946

SPECIMEN COLLECTION
Specimen type:
Plasma or serum
Preferred collection container:
Specimen required:
2 mL of serum or plasma; minimum 0.5 mL.

SPECIMEN PROCESSING
Specimen processing instructions:
Plasma: Centrifuge at 1100-2000 g for a minimum of 10 minutes.
Serum: Allow to clot. Centrifuge at 1100-2000 g for a minimum of 10 minutes. 
Transport temperature:
Refrigerated (preferred) or frozen.
Specimen stability:
Refrigerated: 14 days. Frozen: 6 months.
Rejection criteria:
Stability limits exceeded.

TEST DETAILS
Reference interval:
Females: 4.8-23.3 ng/mL.
Males: 4.0-15.2 ng/mL.
Additional information:
HAMA (Human Anti-Mouse Antibodies) interfere with this test. Patients who have been treated with Mouse Monoclonal Antibodies should not be tested with this procedure.
CPT code(s):
84146
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Prolactin.
Methodology:
Electrochemiluminescence
Clinical significance:
During pregnancy and postpartum lactation, serum prolactin can increase 10- to 20-fold. Exercise, stress and sleep also cause transient increases in prolactin levels. Consistently elevated serum prolactin levels (>30 ng/mL) in the absence of pregnancy and postpartum lactation are indicative of hyperprolactinemia. Hypersecretion of prolactin can be caused by pituatary adenomas, hypothalamic disease, breast or chest wall stimulation, renal failure or hypothyroidism. A number of drugs, including many antidepressants, are also common causes of abnormally elevated prolactin levels. Hyperprolactinemia often results in galactorrhea, amenorrhea, and infertility in females and impotence and hypogonadism in males. Renal failure, hypothyroidism, and prolactin-secreting pituitary adenomas are also common causes of abnormally elevated prolactin levels.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Sheng-Ying (Margaret) Lo, PhD, DABCC    
Review Date: 11/05/2018

Performing Locations

Geisinger Medical Center

Performing laboratory: Automated Chemistry
Technical Lead: Mariana Moyer, Jared Shepherd
Frequency: Daily
Performed stat? No
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