Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

ACETYLCHOLINE RECEPTOR BINDING ANTIBODY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB1508         Geisinger Epic ID: 6981

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
3.5 mL gold-top (serum separator) tube
Specimen required:
1 mL aliquot of serum; minimum 0.5 mL.

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge 10 minutes at 3000 rpm. 
Transport temperature:
Refrigerated (preferred). Room temperature or frozen specimen also acceptable.
Specimen stability:
Room Temperature: 14 days. Refrigerated: 14 days. Frozen: 30 days.
Rejection criteria:
Microbially contaminated. Gross hemolysis. Grossly lipemic.

TEST DETAILS
Interpretation guide:
Negative =0.30 nmol/L
Equivocal 0.31-0.49 nmol/L
Positive =0.50 nmol/L
CPT code(s):
83519
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Acetylcholine Receptor Binding Antibody.
Methodology:
Radioimmunoassay (RIA)
Synonyms:
AChR Binding Antibodies, Quest test code 206, ACETYL
Clinical significance:
Myasthenia Gravis (MG) is an autoimmune neuromuscular disorder characterized by muscle weakness, most commonly due to autoantibody-mediated loss of functional acetylcholine receptors (AChR) in the neuromuscular junction. AChR binding autoantibodies are diagnostic of MG, and are found in 85-90% of MG patients. This assay aids in the differential diagnosis of conditions with MG-like muscle weakness and in monitoring therapeutic response. If binding antibodies are negative, assays for modulating and blocking antibodies should be considered.

Performing Locations

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Set up Sunday-Friday p.m., report available next day.    
Performed stat? No
Locations  |    Search  |    Site Map |   Contact Us
©2000-2021 Geisinger Health System.   All rights reserved.