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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
RUBELLA ANTIBODY (IGM ) |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB3025 Geisinger Epic ID: 15185 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
1 mL serum; minimum 0.6 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and aliquot. | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: 4 days. Refrigerated: 7 days. Frozen: 30 days. | |
Rejection criteria: |
Specimen grossly hemolyzed or lipemic. | |
TEST DETAILS |
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CPT code(s): |
86762 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Immunoassay |
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Synonyms: |
RUBELLA IGM ANTIBODY, RUBELLA ANTIBODY, RUBM, Quest test code 4422
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Clinical significance: |
Rubella is an acute exanthematous viral infection of children and adults. Rash, fever and lymphadenopathy characterize the illness. While many infections are subclinical, this virus has the potential to cause fetal infection with resultant birth defects. In the absence of a current or recent infection, a demonstration of specific IgG on a serum sample is evidence of immunity to rubella. A positive rubella IgM result does not necessarily indicate current or recent infection. Without a history of exposure to rubella or symptoms consistent with rubella, the IgM result may be difficult to interpret. Rubella IgM can be false positive due to other causes (e.g., parvovirus, rheumatoid factor, cytomegalovirus). Rubella IgM may also persist for more than 12 months after vaccination or natural infection. For a serologic diagnosis of congenital rubella in the neonatal period, antibody to rubella virus should be measured in both infant and maternal sera. If IgM is detected in a newborn infant's serum, it is probable that transplacental rubella infection has occurred. | |