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Geisinger Medical Laboratories Test Catalog
GAD65 ANTIBODY, INSULIN DEPENDENT DIABETES |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2334 Geisinger Epic ID: 46333 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
3.5 mL gold-top (serum separator) tube
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Specimen required: |
1 mL aliquot of serum; minimum 0.5 mL. | |
Special notes: |
See Specimen Processing Instructions. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and transfer serum from the cells to a sterile, plastic, screw-capped vial(s). | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: 7 days. Refrigerated: 14 days. Frozen: 28 days. | |
TEST DETAILS |
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CPT code(s): |
86341 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Glutamic acid decarboxylase antibody. | |
Methodology: |
Enzyme-Linked Immunosorbent Assay (ELISA) |
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Synonyms: |
ANTI GAD, GAD65 INSULIN DEPENDENCE AB Quest test code 34878 GADC
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Clinical significance: |
Glutamic Acid Decarboxylase (GAD-65) Antibody is useful to diagnose insulin dependent diabetes mellitus (IDDM, Type I diabetes), to assess risk for development of IDDM, to predict onset of IDDM, and risk of development of related endocrine disorders, e.g., thyroiditis. Before clinical onset, Type I diabetes is characterized by lymphocytic infiltration of the islet cells, and by circulating autoantibodies against a variety of islet cell antigens, including GAD-65, IA-2 (a tyrosine phosphatase-like protein), and insulin autoantibody (IAA). | |