Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

PROTEINASE 3 ANTIBODY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2942         Geisinger Epic ID: 18290

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Interpretation guide:
Negative ≤ 20 Units
Weak Positive 21-30 Units
Moderate to Strong Positive ≥ 31 Units
CPT code(s):
83520
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Antibody detection to proteinase 3 (PR3).
Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms:
ANTI-PROTEINASE 3 ANTIBODY, PR3
ANTI-PR3 ANTIBODY
c-ANCA
Clinical significance:
The presence of anti-PR3 antibodies when used in conjunction with other clinical findings can aid in the assessment of autoimmune vasculitis such as Wegener's granulomatosis.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Stacy Kenyon, PhD, DABCC
   
Review Date: 11/22/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Two days per week, 1st shift.
Performed stat? No
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