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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
PROTEINASE 3 ANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2942 Geisinger Epic ID: 18290 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 0.5 mL serum. | |
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | |
Specimen stability: |
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months. | |
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | |
TEST DETAILS |
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Reference interval: |
Negative <2.0 U/mL | |
Interpretation guide: |
Negative <2.0 U/mL Equivocal 2.0-3.0 U/mL Positive >3.0 U/mL |
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CPT code(s): |
86037 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Antibody detection to proteinase 3 (PR3). | |
Methodology: |
Enzyme Immunoassay (EIA) |
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Synonyms: |
ANTI-PROTEINASE 3 ANTIBODY, PR3 ANTI-PR3 ANTIBODY c-ANCA
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Clinical significance: |
The presence of anti-PR3 antibodies when used in conjunction with other clinical findings can aid in the assessment of autoimmune vasculitis such as Wegener's granulomatosis. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC | |
| Review Date: | 12/13/2022 | |