Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Test Name: Sunquest Test Code Epic Procedure Code Or ID CPT Code:  

LUPUS ANTICOA PNL/INT

ORDERING INFORMATION:
Sunquest Test Code:
LUPACC      Geisinger Epic Procedure Code: LUPACC         Geisinger Epic ID: 26810

SPECIMEN COLLECTION
Specimen type:
Platelet-free plasma AND serum.
Preferred collection container:
Alternate Collection Container:
Other size blue-top (3.2% sodium citrate) tubes (e.g., 1.8 mL, 4.5 mL)
Specimen required:
Three (3) 1 mL aliquots of platelet-free citrated plasma and one (1) 1 mL aliquot of serum.
Special notes:
Collect two (2) 2.7 mL blue-top tubes (3.2% sodium citrate) and one (1) 6 mL red-top tube (nonserum separator).
Patient preparation:
Must be off heparin 48 hours prior to testing; must be off Coumadin 2 weeks prior to testing.

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge clotted red-top tube for 15 minutes at 2500 x g, 1 ml aliquot serum, and blue-top tubes at the designated speed and time to obtain platelet-poor plasma (< 10,000/uL). Remove plasma and re-spin the plasma for 10 minutes at 3000 rpm. Remove the supernatant platelet free plasma into (3) 1 mL aliquots, freeze and transport frozen. 
Transport temperature:
Three (3) aliquots of citrated plasma frozen. One (1) aliquot of serum refrigerated.
Specimen stability:
Frozen: -20°C for 30 days, -70°C for 6 months.
Rejection criteria:
Clotted specimen. Stability limits exceeded.

TEST DETAILS
Reference interval:
See individual test member.
Additional information:
Testing includes interpretation with report.
CPT code(s):
85613, 85610, 85730, 86147 x3, Additional tests if indicated: 85525, 85611, 85597, 86146 x3
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Prothrombin time, lupus sensitive APTT, dilute Russel's viper venom time, and anticardiolipin antibodies. PT/APTT LA mixing studies, platelet neutralization, and beta 2 glycoprotein IgG, IgM ,and IgA if indicated. Pathologist interpretation.
Methodology:
See individual member listings.
Synonyms:
Lupus inhibitor panel with interpretation
Lupus anticoagulant panel with interpretation
Clinical significance:
The persistent presence of a lupus anticoagulant in a patient's plasma increases the risk of a thrombotic event. This test panel includes a battery of tests to rule out its presesnce. An interpretation of tests by a pathologist is included.
Doctoral Director(s:)
Michelle Grant DO    
Review Date: 04/29/2019

Performing Locations

Geisinger Medical Center

Performing laboratory: Coagulation
Technical Lead: Margaret Knowles-Tuchman
Frequency: First shift, twice weekly
Performed stat? No
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