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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
RISPERIDONE AND METABOLITE |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB3013 Geisinger Epic ID: 17751 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Specimen required: |
3 mL aliquot of serum; minimum 1.5 mL. | |
Special notes: |
The use of serum separator tubes is not acceptable. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge 10 minutes at 3000 rpm. | |
Transport temperature: |
Room temperature. | |
Specimen stability: |
Room Temperature: 7 days. Refrigerated: 28 days. Frozen: 60 days. | |
Rejection criteria: |
The use of serum separator tubes (SST) is not acceptable. Submission of an SST will result in cancellation. | |
TEST DETAILS |
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CPT code(s): |
80299 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Risperidone, OH-Risperidone, Risperidone + OH-Risperidone. | |
Methodology: |
Chromatography/Mass Spectrometry |
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Synonyms: |
RISPERIDAL, RISP Quest test code 2339
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Clinical significance: |
Therapeutic drug monitoring for effective therapy. Risperidone is rapidly converted into its hydroxy metabolite in the liver. Peak concentration of risperidone occurs in about 1 hour following oral administration and for 9-hydroxyrisperidone the peak level is reached at 3 hours (17 hours for poor metabolizers). The elimination half-life of risperidone is 3 hours (20 hours for poor metabolizers), and is 21 hours of hydroxyrisperidone (30 hours for poor metabolizers). | |