Geisinger Medical Laboratories Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

HUMAN PAPILLOMA VIRUS, PROBE

Geisinger Epic Procedure Code: LAB2499             Geisinger Epic ID: 21441
       

SPECIMEN COLLECTION
Specimen type:
Genital sources: Cervical specimens collectedin PreservCyt solution or SurePath Preservation Fluid.
Preferred collection container:
Special notes:
See Microbiology Collection Appendix for collection instructions. A PAP smear and/or HPV testing can be performed from the TriPath SurePath Preservative Fluid or Cytyc PreservCyt Solution for ThinPrep Pap. Check expiration date on transport device before use. Specimens must be collected prior to the application of acetic acid or iodine if colposcopic examination is being performed. Any specimen collected with a Qiagen (Digene) Cervical Sampler specimen transport will be sent to a reference laboratory for testing.

SPECIMEN PROCESSING
Transport temperature:
Room temperature (2-30°C acceptable)
Specimen stability:
TriPath SurePath Preservative Fluid: Room temperature for 4 weeks, 2-8°C for 6 months.
Cytyc PreservCyt: 2-30°C for 3 months.
Rejection criteria:
Improperly labeled/identified specimens. Expired transport media. Specimens stored or transported at incorrect temperature.

TEST DETAILS
Reference interval:
Negative for high/intermediate risk Human Papillomavirus E6/E7 messenger RNA (mRNA).
Critical values/courtesy alerts:
Positive for high/intermediate risk Human Papillomavirus E6/E7 messenger RNA (mRNA.
CPT code(s):
87624
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Nucleic acid amplification and detection of intermediate/high-risk Human Papillomavirus types. High/intermediate risk includes high/intermediate risk HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68.
Methodology:
Hybrid Capture with Signal Amplification
Hybridization Production Assay
Synonyms:
MPHPV, DNA PROBE
RNA PROBE
HPV PROBE, HPV TARGET
HPV HYBRIDE CAPTURE, REFLEXIVE HPV, HPV SCREEN
HUMAN PAPILLOMAVIRUS PROBE, AMPLIFIED HPV, AMPLIFIED
HUMAN PAPILLOMAVIRUS
HIGH RISK HPV, SUREPATH HPV, THINPREP HPV
THINLAYER HPV
THINPREP, THINLAYER
Clinical significance:
Use this test to detect high/intermediate risk types of HPV. HPV is associated with the development of cervical cancer in women.
Doctoral Director(s:)
Donna Wolk PhD, D(ABMM), Raquel Martinez, PhD, D(ABMM)    
Review Date: 12/31/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: Microbiology
Technical Lead: Francis Tomashefski
Frequency: Monday through Friday (first shift)
Performed STAT? No
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