Geisinger Medical Laboratories Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  


Geisinger Epic Procedure Code: LAB2499             Geisinger Epic ID: 21441

Specimen type:
Genital sources: Cervical specimens collected in PreservCyt solution or SurePath Preservation Fluid.
Preferred collection container:
Special notes:
A PAP smear and/or HPV testing can be performed from the SurePath Preservative Fluid or ThinPrep PreservCyt Vial. Check the expiration date on the collection device before use. Specimens must be collected before the application of acetic acid or iodine if colposcopic examination is being performed.

Transport temperature:
Room temperature (2-30°C acceptable)
Specimen stability:
TriPath SurePath Preservative Fluid: Room temperature for 4 weeks, 2-8°C for 6 months.
Cytyc PreservCyt: 2-30°C for 3 months.
Rejection criteria:
Improperly labeled/identified specimens. Expired transport media. Specimens stored or transported at incorrect temperature.

Reference interval:
Negative for high/intermediate risk Human Papillomavirus E6/E7 messenger RNA (mRNA).
Critical values/courtesy alerts:
Positive for high/intermediate risk Human Papillomavirus E6/E7 messenger RNA (mRNA).
CPT code(s):
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Nucleic acid amplification and detection of intermediate/high-risk Human Papillomavirus types. High/intermediate risk includes high/intermediate risk HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68.
Transcription-Mediated Amplification (TMA)
MPHPV, DNA Probe, RNA Probe, HPV Probe, HPV Target, Reflexive HPV, HPV Screen, Human Papillomavirus Probe, Amplified HPV, Amplified Human Papillomavirus, High Risk HPV, SurePath HPV, ThinPrep HPV, Thinlayer HPV, ThinPrep, ThinLayer, hrHPV
Clinical significance:
Use this test to detect high/intermediate risk types of HPV. HPV is associated with the development of cervical cancer in women.
Doctoral Director(s:)
Donna Wolk PhD, D(ABMM)
Julie Hirschhorn, PhD, HCLD(ABB)    
Review Date: 06/06/2024

Performing Locations

Geisinger Medical Center

Performing laboratory: Microbiology
Technical Lead: Barbara Heiter, Francis Tomashefski
Frequency: Monday through Friday, 1st shift
Performed STAT? No
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