Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Test Name: Sunquest Test Code Epic Procedure Code Or ID CPT Code:  

ANTI-CENTROMERE AB

ORDERING INFORMATION:
Sunquest Test Code:
ACAB      Geisinger Epic Procedure Code: 86255.05         Geisinger Epic ID: 17575

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL.

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 96 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Reference interval:
< 1:40
Additional information:
Centromere body is a specific ANA pattern. It is not necessary to order an ANA and a centromere together. If a centomere pattern is observed in a sample ordered for an ANA, it will be reported.
CPT code(s):
86255
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Antibody detection and titer if positive.
Methodology:
Indirect Immunofluorescent Antibody (IFA)
Synonyms:
Centromere Antibody
CREST Syndrome
Clinical significance:
Centromere antibody is a specific ANA (antinuclear antibody) pattern that is diagnostic for the form of scleroderma known as CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly and telangiectasia).
Doctoral Director(s:)
Stacy Kenyon, PhD, DABCC
Hoi-Ying Elsie Yu, PhD, DABCC    
Review Date: 10/24/2018

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Monday - Friday, 1st shift
Performed stat? No
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