Geisinger Medical Laboratories Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  


Geisinger Epic Procedure Code: LAB4887             Geisinger Epic ID: 186352

Specimen type:
Whole blood
Preferred collection container:
Alternate Collection Container:
6 mL pink-top K2 EDTA tube
Special notes:
The test is indicated for use in pediatric patients (>3 months to <18 years of age) presenting to the emergency department, with suspected acute bacterial or viral infections, who have had symptoms and fever within the last 7 days. The test is currently only offered at Geisinger Medical Center.

Specimen processing instructions:
Send unspun blood collection immediately to testing laboratory. The blood must be received within 90 minutes of collection. 
Transport temperature:
Room temperature (15-30°C). Transport immediately via pneumatic tube system to the laboratory after collection.
Specimen stability:
Testing must be performed within 90 minutes of collection if stored at room temperature (15-30°C). Refrigerate the specimen upon arrival into the laboratory. Specimen may be stored at 2-8°C for up to 4 hours.
Rejection criteria:
Specimens stored or transported at incorrect temperature, frozen, stability limits exceeded, improper collection tube used, insufficient volume, improperly labeled/identified specimens (2 identifiers are required). The test is not intended for patients with the following conditions: <3 months or >17 years of age; pregnant women; active inflammatory disease; congenital or acquired immune deficiency; chronic fungal or parasitic infection; infection with human immunodeficiency virus (HIV); Hepatitis B virus (HBV); Hepatitis C virus (HCV); infection with active tuberculosis (TB); significant trauma or burns in the last 7 days; patients that have undergone major surgery in the last 7 days; or active malignancy.

Critical values/courtesy alerts:
None The test is used in conjunction with other clinical and diagnostic criteria.
Additional information:
The test results include measurements of 3 human proteins combined into one risk stratification score. 1. TNF -Related Apoptosis-Inducing Ligand (TRAIL). 2. Interferon Gamma Induced Protein 10 (IP-10). 3. C-Reactive Protein. (CRP)
CPT code(s):
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Automated semi-quantitative immunoassay.
Bacterial Viral screen, Bacterial, Viral, Screen, Markers, Risk, Stratification, BV, Biomarker
Clinical significance:
This test measures three (host) proteins: TRAIL, IP-10, and CRP) found in whole blood samples. Test results are intended for use in conjunction with clinical assessments and other laboratory findings as an aid to differentiate bacterial from viral infections.
Doctoral Director(s:)
Donna Wolk PhD, D(ABMM)
Julie Hirschhorn, PhD, HCLD(ABB)    
Review Date: 02/13/2024

Performing Locations

Geisinger Medical Center

Performing laboratory: Microbiology
Technical Lead: Barbara Heiter, Francis Tomashefski
Frequency: Daily, all shifts
Performed STAT? Yes
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