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Geisinger Medical Laboratories Test Catalog
DRUG MONITORING, TAPENTADOL, QUANTITATIVE URINE |
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Geisinger Epic Procedure Code: LAB4815
Geisinger Epic ID: 184237
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SPECIMEN COLLECTION |
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Specimen type: |
Urine | |
Preferred collection container: |
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Specimen required: |
20 mL random urine; minimum 5 mL. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Aliquot 20mL urine and refrigerate. | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: 5 days. Refrigerated: 7 days. Frozen: 30 days. | |
Rejection criteria: |
Preserved samples are unacceptable | |
TEST DETAILS |
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CPT code(s): |
80372 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Mass Spectrometry |
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Synonyms: |
Quest code 39405
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Clinical significance: |
Tapentadol is approved for the treatment of moderate to severe acute pain. Due to its dual mechanism of action as an opioid agonist and norepinephrine reuptake inhibitor, there is potential for ON LABEL for chronic pain. The test is a definitive assay using liquid chromatography mass spectroscopy (LC/MS/MS) methodology. Therapeutic urine drug monitoring of tapentadol is important for ensuring compliance to treatment strategies. Urine or oral fluid are the specimens of choice for routine monitoring of patients taking prescription drugs. Use of serum/plasma should be limited to anuretic patients, or where a patient's clinical appearance does not coincide with their prescribed medications. No single monitoring approach provides adequate information about the pattern or dose of patient drug use. Safest prescribing habits should include a combination of tools and laboratory test results to correctly detect drug use patterns. Quantitative values cannot be used to assess the drug dose, because the drug is extensively metabolized and excreted in the urine.” | |