Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

  

CENTROMERE ANTIBODY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB1237         Geisinger Epic ID: 52873

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Specimen required:
0.5 mL serum; minimum 0.2 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) or frozen specimen also acceptable.
Specimen stability:
Room temperature: 8 hours. Refrigerated (2-8°C): 72 hours. Frozen: 6 months

TEST DETAILS
Reference interval:
Negative <7 U/mL
Interpretation guide:
Negative: <7 U/mL
Equivocal: 7-10 U/mL
Positive: >10 U/mL
CPT code(s):
86235
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Enzyme Immunoassay (EIA)
Clinical significance:
The presence of centromere B antibodies in correlation with clinical findings can aid in the diagnosis of scleroderma (CREST syndrome). Centromere antibodies are found in 70-90% of patients with CREST syndrome, 10-20% of patients with Raynaud's phenomenon and primary biliary cirrhosis.
Doctoral Director(s:)
Hoi-Ying Elsie Yu PhD, DABCC    
Review Date: 07/22/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Monday-Friday 1st shift
Performed STAT? No
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