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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
LYME DISEASE ANTIBODY INDEX FOR CNS INFECTION |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB4087 Geisinger Epic ID: 168262 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum AND cerebrospinal fluid | |
Preferred collection container: |
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Specimen required: |
2 mL (min 1 mL) serum AND and 2 mL (min 1 mL) CSF | |
Special notes: |
Collect BOTH serum AND CSF. It is preferred that the collection date and time be the same for both the CSF and Serum. Serum can be drawn within 24 hours of the CSF, but this is not recommended | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
CSF: Do not centrifuge. Transport Room temperature. Serum: Centrifuge within 1 hour of collection and transfer serum specimens to sterile, plastic, screw-capped vial(s). Transport Room temperature | |
Transport temperature: |
Room temperature. | |
Specimen stability: |
Room temperature: 7 days, Refrigerated: 14 days, Frozen: 30 days. | |
Rejection criteria: |
CSF and serum collected greater than 24 hours apart | |
TEST DETAILS |
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CPT code(s): |
82040, 82042, 82784 x2, 86618 x4 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Lyme Disease Antibody Index, Control Antibody Index, Albumin Ratio | |
Methodology: |
Enzyme-Linked Immunosorbent Assay (ELISA) Nephelometry |
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Synonyms: |
Quest test code 34194
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Clinical significance: |
The Lyme disease antibody index is used as an aid for diagnosing neuroborreliosis. The assay requires paired serum and CSF. A result set of lyme disease antibody index >1.2, control antibody index <1.0, and albumin ratio <0.0078 provides strong evidence of intrathecal synthesis of b. Burgdorferi antibodies and supports the diagnosis of neuroborreliosis. | |