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Geisinger Medical Laboratories Test Catalog
HEPATITIS D VIRUS RNA, QUANTITATIVE, REAL-TIME PCR |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1350 Geisinger Epic ID: 53325 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
2 mL serum; minimum 0.6 mL. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Separate serum from whole blood within 24 hours. Freshly collected whole blood may be stored at 2-25°C for up to 24 hours before separation. Serum should be transported frozen on dry ice in plastic screw cap vials. | |
Transport temperature: |
Frozen. | |
Specimen stability: |
Room temperature: 24 hours. Refrigerated: 48 hours. Frozen: 30 days. | |
Rejection criteria: |
Serum not separated from whole blood. | |
TEST DETAILS |
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Additional information: |
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics Infectious Disease. It has not been cleared or approved by the U.S. Food and | |
CPT code(s): |
87799 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Real-time Polymerase Chain Reaction (PCR) |
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Synonyms: |
Quest test code 37889, Hep D QN PCR
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Clinical significance: |
Hepatitis D virus (HDV) infection requires the surface antigen from HBV and may occur as an acute infection with HBV or as a superinfection of a chronic HBV infection. HDV should be considered in any individual who tests positive for the HBV surface antigen (HBsAg). The presence of HDV RNA in the serum reflects viral replication in the liver. HDV-HBV co-infection is considered the most severe form of chronic viral hepatitis due to more rapid progression towards liver-related death and hepatocellular carcinoma. HDV RNA, quantitative real-time PCR can assist with diagnosis of HDV infection as well as monitoring of treatment. | |