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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
PARANEOPLASTIC ANTIBODY EVALUATION WITH REFLEX TO TITER AND LB, BASIC, CSF |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1344 Geisinger Epic ID: 53301 | |
SPECIMEN COLLECTION |
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Specimen type: |
CSF | |
Preferred collection container: |
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Specimen required: |
3.8 mL CSF; minimum 2.4 mL | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Refrigerated (cold packs). | |
Specimen stability: |
Room temperature: 48 hours. Refrigerated: 14 days. Frozen: 21 days. | |
TEST DETAILS |
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Additional information: |
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. | |
CPT code(s): |
86255 (x10), 86341 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
If the Paraneoplastic Ab Screen, IFA is positive for Aquaporin-4 Ab, IFA, then Aquaporin-4 (AQP4) Antibody (IgG), CBA, CSF will be performed at an additional charge (CPT code(s) 86255). If Aquaporin-4 (AQP4) Antibody (IgG), CBA result is positive, then a titer will be performed at an additional charge (CPT code(s) 86256) . If the Paraneoplastic Ab Screen, IFA is positive for ANNA3 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256) . If the Paraneoplastic Ab Screen, IFA is positive for PCA2 Ab IFA, then a titer will be performed at an additional charge (CPT code(s) 86256). If the Paraneoplastic Ab Screen, IFA is indeterminate or positive for ANNA1, ANNA2, PCA1, PCA-Tr (DNER), Amphiphysin, GAD65, or CRMP5 (CV2) antibodies, then Paraneoplastic Antibody, Line Blot will be performed at an additional charge (CPT code(s) 84182 x7, 86341). If the Paraneoplastic Ab Screen, IFA is positive for NMDAR1, LGI-1, CASPR2, AMPAR1, AMPAR2, GABA receptor B, or Voltage Gated Antibodies, then Paraneoplastic Antibody, CBA IFA will be performed at an additional charge (CPT code(s) 86255 x6). If Paraneoplastic Antibody, CBA IFA is positive for NMDAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for AMPAR1 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA, IFA is positive for AMPAR2 Ab CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for GABA receptor B Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for LGI-1 Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If Paraneoplastic Antibody, CBA IFA is positive for CASPR2 Ab, CBA, then a titer will be performed at an additional charge (CPT code(s) 86256). If the Paraneoplastic Ab Screen, IFA is positive for LGI-1, CASPR2, or Voltage Gated Antibodies, then Voltage-Gated Potassium Channel (VGKC) Antibody, CSF will be performed at an additional charge (CPT code(s) 83519). | |
Methodology: |
See individual member listings. |
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Synonyms: |
Quest test code 94536, Par Eval Csf
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Clinical significance: |
Fluorescent staining patterns on multiple neuronal and non-neuronal tissues identify likely autoantibodies present. Reflex testing to western line blot, cell based indirect immunofluorescent assay or radioimmunoassay may define specific autoantibodies. | |