Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

PROSTATIC ACID PHOSPHATASE (PAP)

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2930         Geisinger Epic ID: 17214

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
1 mL aliquot of serum; minimum 0.5 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot.
Special notes:
Samples should be obtained before rectal examination, biopsy, prostatectomy, or prostatic massage, since manipulating the prostate gland may lead to elevated PAP levels persisting up to 24-48 hours.

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge 10 minutes at 3000 rpm. 
Transport temperature:
Frozen.
Specimen stability:
Room Temperature: 24 hours. Refrigerated: 24 hours. Frozen: 4 weeks.
Rejection criteria:
Grossly hemolyzed samples. Stability limits exceeded.

TEST DETAILS
Reference interval:
Male: <2.8 ng/mL
Female: Not established
Additional information:
PAP values from different assay methods cannot be used interchangeably. This assay was performed using the DPC Chemiluminescence method.
CPT code(s):
84066
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Prostatic acid phosphatase.
Methodology:
Immunoassay
Synonyms:
ACID PHOS, PROSTATIC, PAP
Quest test code 208
Clinical significance:
High concentrations of acid phosphatase are found in the prostate gland. Significant amounts are also found in platelets, bone, spleen, kidney and liver. Prostatic Acid Phosphatase (PAP) is a component of total acid phosphates and is a major constituent in seminal fluid and is also secreted in the urine. PAP is normally found in serum in very low levels. PAP measurement has found clinical application in the management of prostatic cancer patients. Serum PAP measurements have been useful in monitoring remission or relapse of a prostatic malignancy and in assessing the effectiveness of various treatment regimes. Thus, normalization in serum PAP levels has been observed following successful therapeutic intervention, while recurrent or residual disease has been associated with elevated levels of PAP.

Performing Locations

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Set up: Monday-Saturday. Report available: 1 days    
Performed stat? No
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