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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
OXYCODONE AND METABOLITE, QUANTITATIVE, SERUM |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1077 Geisinger Epic ID: 52233 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Specimen required: |
5 mL serum; minimum 3 mL | |
Special notes: |
Do not use serum separator tubes. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and aliquot. | |
Transport temperature: |
Room temperature. | |
Specimen stability: |
Room temperature: 7 days Refrigerated: 7 days Frozen: 7 days. | |
Rejection criteria: |
Serum separator tubes are not acceptable. | |
TEST DETAILS |
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CPT code(s): |
80365 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Oxycodone and oxymorphone. | |
Methodology: |
Chromatography/Mass Spectrometry |
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Synonyms: |
Quest test code 18885, Oxycodone Sr
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Clinical significance: |
For therapeutic drug monitoring of oxycodone (Oxycontin®, Percocet®, Percodan®). Oxycodone is a semisynthetic opioid analgesic. Steady state concentration is reached in 24-36 hours after initiation of therapy. Elimination half-life of oxycodone is 4.5 hours for controlled release and 3.2 hours for immediate release formulations. Peak plasma concentration of oxycodone is 11, 21, 39, 99, or 156 ng/mL after a single oral dose of 10, 20, 40, 80, or 160 mg respectively. Oxymorphone is a minor but active metabolite of oxycodone that is present at lower concentration in the circulation. Therapeutic concentrations for oxymorphone have not been established. | |