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Geisinger Medical Laboratories Test Catalog
HUMAN TRANSFORMING GROWTH FACTOR BETA 1 (TGF-B1) |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1057 Geisinger Epic ID: 52153 | |
SPECIMEN COLLECTION |
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Specimen type: |
Plasma | |
Preferred collection container: |
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Specimen required: |
1 mL plasma; minimum 0.25 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge for 15 minutes at 1000 x g within 30 minutes of collection. Centrifuge plasma again at 3000 x g for 10 minutes for complete platelet removal. Freeze at -20°C. Transport container: Plastic screw-cap vial | |
Transport temperature: |
Frozen. | |
Specimen stability: |
Room temperature: Unacceptable. Refrigerated: 48 hours. Frozen -20° C: 14 days. Frozen -70° C: 30 days. | |
Rejection criteria: |
Hemolyzed specimens. Hyperlipemic specimens. Specimens with particulate matter or microbial contamination. Specimens outside of listed stability. | |
TEST DETAILS |
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Additional information: |
The performance characteristics of the listed assay was validated by BioAgilytix Diagnostics. The US FDA has not approved or cleared this test. The results of this assay can be used for clinical diagnosis without FDA approval. BioAgilytix Diagnostics is a CLIA certified, CAP accredited laboratory for performing high complexity assays such as this one. | |
CPT code(s): |
83520 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Enzyme-Linked Immunosorbent Assay (ELISA) |
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Synonyms: |
Quest test code 91238, TGFb1
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Clinical significance: |
Transforming Growth Factor (TGF) plays a crucial role in tissue regeneration, cell differentiation, embryonic development, and regulation of the immune system. Transforming growth factor beta is found in hematopoietic (blood-forming) tissue and initiates a signaling pathway that suppresses the early development of cancer cells. It enhances the deposition of extracellular matrix and may play potential role in wound healing and cirrhosis formation. Many cells synthesize TGF-b and almost all of them have specific receptors for this peptide. | |