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Geisinger Medical Laboratories Test Catalog
UGT1A1 GENE POLYMORPHISM (TA REPEAT) |
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Geisinger Epic Procedure Code: LAB1054
Geisinger Epic ID: 52141
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SPECIMEN COLLECTION |
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Specimen type: |
Whole blood | |
Preferred collection container: |
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Alternate Collection Container: |
3 mL lavender-top (K2 EDTA) tube
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Specimen required: |
5 mL whole blood; minimum 3 mL. | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Room temperature. | |
Specimen stability: |
Room temperature: 8 days. Refrigerated: 8 days. Frozen: Unacceptable. Ship immediately to maintain sample stability. | |
Rejection criteria: |
Gross hemolysis, clotted blood, received frozen. | |
TEST DETAILS |
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Additional information: |
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes. | |
CPT code(s): |
81350 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Fluorescent Polymerase Chain Reaction |
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Synonyms: |
Quest test code 17813, UGT1A1 Gene, Irinotecan Toxicity,Colorectal Cancer (CRC),Irinotecan Metabolism,Gilbert's Syndrome,UPD-glucuronosyltransferase 1A1 (UGT1A1)
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Clinical significance: |
This assay is intended for selection of colorectal cancer patients who would benefit most and experience the least toxicity from 5-FU, oxalipatin and Irinotecan chemotherapy by determining the individual patient genotypes to guide chemotherapy choices in advanced stage colorectal cancer. | |