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Geisinger Medical Laboratories Test Catalog
SOLUBLE LIVER ANTIGEN (SLA) AUTOANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1050 Geisinger Epic ID: 52125 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
1 mL serum; minimum 0.3 mL. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and aliquot. | |
Transport temperature: |
Refrigerated (cold packs). | |
Specimen stability: |
Room temperature: 48 hours. Refrigerated: 8 days. Frozen: 28 days. | |
Rejection criteria: |
Gross hemolysis. Lipemia. | |
TEST DETAILS |
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CPT code(s): |
83520 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Immunoassay |
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Synonyms: |
Quest test code 38928, Soluble Live
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Clinical significance: |
Anti-soluble liver antigen antibodies are detected in 10-30% of patients with type 1 autoimmune hepatitis (AIH), but not in patients with type 2 AIH, primary sclerosing cholangitis or primary biliary cirrhosis. The antibody is directed against a UGA suppressor tRNA-associated protein. In some patients with AIH, this antibody may be the only autoantibody detected by current assays. | |