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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
FISH, MYELOID LYMPHOID LEUKEMIA, GENE REARRANGEMENT, PEDIATRIC |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: FISMLL Geisinger Epic ID: 145810 | |
SPECIMEN COLLECTION |
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Specimen type: |
Bone marrow or whole blood | |
Preferred collection container: |
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Alternate Collection Container: |
Bone marrow culture transport media
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Specimen required: |
3 mL (minimum 1 mL) bone marrow in bone marrow transport media or green-top sodium heparin tube OR 5 mL (minimum 3 mL ) whole blood in green-top sodium heparin tube. | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Room temperature. | |
Specimen stability: |
Transport immediately after collection. Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject. | |
Rejection criteria: |
Frozen specimens unacceptable | |
TEST DETAILS |
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Additional information: |
If results are not possible, the test order may be canceled and replaced with a Cytogenetics Communication. | |
CPT code(s): |
88271 x 2, 88275 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Fluorescence In Situ Hybridization (FISH) |
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Synonyms: |
KM2TA 11Q23 Rearrangement,MLL, Quest test code 36055 FISMLL
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Clinical significance: |
This test is performed to detect the rearrangements of MLL (KMT2A;11q23) gene by FISH(fluorescence in situ hybridization). MLL rearrangements have been observed in hematologic neoplasms of either lymphoid or myeloid origin. | |