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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
THYROGLOBULIN AND THYROGLOBULIN ANTIBODY FOR TUMOR MONITORING |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB3157 Geisinger Epic ID: 56526 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
Gold-top (serum separator) microcollection tube
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Specimen required: |
2 mL serum; minimum 1.5 mL | |
Special notes: |
If collecting specimen in microcollection tubes, collect 3 FULL serum separator microcollection tubes. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge within 2 hours of collection and submit one (1) full 3.5 mL gold-top serum separator tube. Aliquot also acceptable (1.5 mL minimum). | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
Thyroglobulin Tumor Monitoring: 5 days refrigerated and 28 days frozen. Thyroglobulin AB Tumor Monitoring: 3 days refrigerated and 28 days frozen |
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Rejection criteria: |
Stability limit exceeded. | |
TEST DETAILS |
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Reference interval: |
Thyroglobulin Tumor Monitoring: See report Thyroglobulin AB Tumor Monitoring: < 22 U/mL |
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Additional information: |
Thyroglobulin quantified by LC-MS/MS must be added on within 7 days from when results are released. | |
CPT code(s): |
86800, 84432 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Thyroglobulin Tumor Monitoring and Thyroglobulin AB Tumor Monitoring | |
Methodology: |
Chemiluminescence |
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Synonyms: |
TPTM
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Clinical significance: |
Thyroglobulin is used to monitor postoperative residual or recurrent differentiated thyroid cancers. Up to 30 percent of this patient population, however, develops autoantibodies to thyroglobulin. These autoantibodies may interfere with immunometric thyroglobulin assay and result in underestimation of thyroglobulin. When autoantibodies to thyroglobulin are present at or above 22 U/mL, thyroglobulin quantified by LC-MS/MS is recommended. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu, PhD, DABCC Sheng-Ying (Margaret) Lo, PhD, DABCC |
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| Review Date: | 12/14/2022 | |