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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
MITOCHONDRIA (M2) ANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2688 Geisinger Epic ID: 34848 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 0.5 mL serum. | |
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | |
Specimen stability: |
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months. | |
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | |
TEST DETAILS |
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Reference interval: |
Negative <4 U/mL | |
Interpretation guide: |
Negative <4 U/mL Equivocal 4-6 U/mL Positive >6 U/mL |
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CPT code(s): |
86381 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Antibody detection to PBC IGA/IGG antibody. | |
Methodology: |
Enzyme Immunoassay (EIA) |
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Synonyms: |
AMA, Anti-Mitochondrial Antibody Primary biliary cirrhosis; gp210 antibody; sp100 antibody PBC IGG/IGA antibody PBC
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Clinical significance: |
Mitochondrial antibody (M2) is present in approximately 95% of patients with Primary Biliary Cirrhosis (PBC). | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC | |
| Review Date: | 07/12/2022 | |