Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

VALPROIC ACID LEVEL

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3230         Geisinger Epic ID: 14240

SPECIMEN COLLECTION
Specimen type:
Plasma or serum
Preferred collection container:
Specimen required:
2 mL aliquot of plasma or serum; minimum 0.2 mL
Patient preparation:
Collect just prior to next dose.

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to serum clot. Centrifuge to separate serum or plasma. 
Transport temperature:
Refrigerated (preferred) or frozen.
Specimen stability:
Room temperature: 2 days. Refrigerated: 1 week. Frozen: 4 weeks.
Rejection criteria:
Stability limits exceeded.

TEST DETAILS
Reference interval:
50-100 mcg/mL
Critical values/courtesy alerts:
Above 121 mcg/mL.
Additional information:
Significant interference with this procedure may occur in patients with antibodies induced during treatment with mouse monoclonal antibodies.
CPT code(s):
80164
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Immunoassay
Synonyms:
Depakene, Depakote, VALP, Valproate
Clinical significance:
Valproic acid is used as an anticonvulsant to treat certain types of seizures, to prevent migraine headaches, and to treat various psychiatric illnesses such as bipolar disorder and aggression. Drugs that compete for protein-binding sites with valproic acid can increase the concentration of valproic acid. Therapeutic drug monitoring is useful to optimize dose. Measurement of the free concentration is useful if toxicity is suspected.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Sheng-Ying (Margaret) Lo, PhD, DABCC    
Review Date: 12/24/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Automated Chemistry
Technical Lead: Mariana Moyer, Jared Shepherd
Frequency: Daily, Monday - Sunday
Performed stat? Yes

Geisinger Wyoming Valley Medical Center

Performing laboratory: ATL+
Technical Lead: Sarah McGowan    
Frequency: Daily, all shifts    
Performed stat? No

Geisinger Community Medical Center

Performing laboratory: Chemistry
Technical Lead: Ann Mack, Deborah Dempsey  
Frequency: Daily, all shifts    
Performed stat? Yes
Locations  |    Search  |    Site Map |   Contact Us
©2000-2021 Geisinger Health System.   All rights reserved.