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Geisinger Medical Laboratories Test Catalog
VMA (VANILLYLMANDELIC ACID), 24-HOUR URINE WITH CREATININE |
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Geisinger Epic Procedure Code: LAB3262
Geisinger Epic ID: 14452
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SPECIMEN COLLECTION |
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Specimen type: |
24-hour urine collected with 25 mL 6N HCl (preferred) | |
Preferred collection container: |
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Specimen required: |
10 mL from 24-hour urine collection in urine bullet; minimum 5 mL | |
Special notes: |
This test needs immediate acidification and can only be collected at Hospital sites. | |
Patient preparation: |
Patient should avoid alcohol, coffee, tea, tobacco (including use of nicotine patch), bananas, citrus fruits and strenuous exercise prior to collection. It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Lab personnel (to be determined per site) will test the pH of the urines and adjust to less than 3.0 using 6N HCl before Referred Testing ships the specimen. Record 24-hour urine volume and patient's age on test request form and urine vial. | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: 10 days. Refrigerated: 14 days. Frozen: 1 year. | |
Rejection criteria: |
Preserved urine received refrigerated with pH > 3. | |
TEST DETAILS |
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CPT code(s): |
82570, 84585 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
VMA, creatinine | |
Methodology: |
High Performance Liquid Chromatography (HPLC) |
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Synonyms: |
Quest test code 39517, Vanillylmandelic Acid, VMA24
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Clinical significance: |
Urinary vanillylmandelic acid is useful in diagnosing neuroblastoma, one of the most common tumors in the pediatric population. | |