Geisinger Medical Laboratories Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  


Geisinger Epic Procedure Code: LAB1941             Geisinger Epic ID: 7283

Specimen type:
Serum (preferred) or sodium citrate plasma.
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
2.7 mL blue-top (3.2% sodium citrate) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL

Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

Reference interval:
Cardiolipin IgG: Negative < 10 GPL-U/mL
Cardiolipin IgM: Negative <10 MPL-U/mL
Interpretation guide:
Cardiolipin IgG:
    Negative <10 GPL-U/mL
    Weak Positive 10-40 GPL-U/mL
    Positive >40 GPL-U/mL
Cardiolipin IgM:
    Negative <10 MPL-U/mL
    Weak Positive 10-40 MPL-U/mL
    Positive >40 MPL-U/mL
Additional information:
Sodium citrate plasma has been validated for use with this assay for those patients ordered for Anti-Lupus Coagulation panels (LUPACP or LUPACC) without an available serum sample.
CPT code(s):
86147 x2
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Cardiolipin Antibody IgG, Cardiolipin Antibody IgM.
Enzyme Immunoassay (EIA)
Anticardiolipin antibody panel, CARDAB
Antiphospholipid antibody panel
Antiphospholipid AB
ACA antibody panel, ACL antibody panel
Cardiolipin antibody
Clinical significance:
The presence of cardiolipin antibodies when used in conjunction with clinical findings and other laboratory tests can aid in assessing the risk of thromboembolic disease in patients with systemic lupus erythematosus (SLE) or primary anti-phospholipid syndrome (APS). Anticardiolipin/beta-2 glycoprotein antibodies must be detected on 2 or more occasions at least 12 weeks apart to fulfill the laboratory diagnostic criteria for Antiphospholipid Syndrome.
Doctoral Director(s:)
Hoi-Ying Elsie Yu PhD, DABCC, FADLM    
Review Date: 12/13/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Two days per week, 1st shift.
Performed STAT? No
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