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Geisinger Medical Laboratories Test Catalog
HE4, OVARIAN CANCER MONITORING |
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Geisinger Epic Procedure Code: LAB2404
Geisinger Epic ID: 45690
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SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
3.5 mL gold-top (serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL | |
Special notes: |
Sample must be received in the lab in less than 1 hour so it can be processed. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Sample collected in a red-top tube must be allowed to clot for at least 30 minutes but no longer than 1 hour. | |
Transport temperature: |
Frozen. | |
Specimen stability: |
Room temperature: 48 hours. Refrigerated: 72 hours. Frozen: 28 days. | |
Rejection criteria: |
Gross hemolysis. Lipemia. Icteric specimens. Presence of fibrin, RBCs or other particulate matter. Obvious microbial contamination. | |
TEST DETAILS |
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CPT code(s): |
86305 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Methodology: |
Chemiluminescent Microparticle Immunoassay |
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Synonyms: |
Quest code 16500, Human Epididymis Protein 4 HE4OCM
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Clinical significance: |
The percentage increase in HE4 values has been used as an aid in monitoring recurrence or progressive disease in patients with invasive epithelial ovarian cancer. Currently there is no clinically accepted cut-off for use in monitoring cancer progression in epithelial ovarian cancer subjects with this assay. Serial testing for patient HE4 assay values should be used in conjunction with methods used for monitoring ovarian cancer. | |