Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Test Name: Sunquest Test Code Epic Procedure Code Or ID CPT Code:  

HE4, OVARIAN CANCER MONITORING

ORDERING INFORMATION:
Sunquest Test Code:
HE4OCM      Geisinger Epic Procedure Code: HE4OCM         Geisinger Epic ID: 45690

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
3.5 mL gold-top (serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL
Special notes:
Sample must be received in the lab in less than 1 hour so it can be processed.

SPECIMEN PROCESSING
Specimen processing instructions:
Sample collected in a red-top tube must be allowed to clot for at least 30 minutes but no longer than 1 hour. 
Transport temperature:
Frozen.
Specimen stability:
Room temperature: 48 hours. Refrigerated: 72 hours. Frozen: 28 days.
Rejection criteria:
Gross hemolysis. Lipemia. Icteric specimens. Presence of fibrin, RBCs or other particulate matter. Obvious microbial contamination.

TEST DETAILS
CPT code(s):
86305
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Chemiluminescent Microparticle Immunoassay
Synonyms:
Quest code 16500, Human Epididymis Protein 4
Clinical significance:
The percentage increase in HE4 values has been used as an aid in monitoring recurrence or progressive disease in patients with invasive epithelial ovarian cancer. Currently there is no clinically accepted cut-off for use in monitoring cancer progression in epithelial ovarian cancer subjects with this assay. Serial testing for patient HE4 assay values should be used in conjunction with methods used for monitoring ovarian cancer.

Performing Locations

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Monday, Wednesday, Friday morning    
Performed stat? No
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