Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

ENDOMYSIAL ANTIBODY SCREEN (IGA), REFLEX TO TITER

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2216         Geisinger Epic ID: 45693

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
3.5 mL gold-top (serum separator) tube
Specimen required:
1 mL serum; minimum 0.3 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge and aliquot 
Transport temperature:
Refrigerated.
Specimen stability:
Room temperature: 4 days. Refrigerated: 21 days. Frozen: 21 days.

TEST DETAILS
Additional information:
If Endomysial Antibody (IgA) Screen is abnormal, Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86256).
CPT code(s):
86255
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Immunofluorescence Assay
Synonyms:
Quest test code 15064
ENDOAB
Clinical significance:
The presence of anti-endomysial (EMA) IgA antibodies has been shown to correlate with gluten-sensitive enteropathy such as celiac disease (CD) and dermatitis herpetiformis (DH). EMA is detected primarily by IFA, using monkey esophagus as a substrate and observing fluorescence of the endomysial lining. Patients with CD and DH can also demonstrate antibodies to reticulin and gliadin, though EMA-IgA seems to be the most specific marker (specifically 94-100%).

Performing Locations

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Tuesday-Saturday morning    
Performed stat? No
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