Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

DOUBLE STRANDED DNA ANTIBODY, INDIRECT IMMUNOFLUORESCENCE ASSAY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2195         Geisinger Epic ID: 41802

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) or frozen specimen also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 72 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Reference interval:
<1:10
CPT code(s):
86225
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Antibody detection and titer if positive.
Methodology:
Indirect Immunofluorescent Antibody (IFA)
Synonyms:
Anti-DNA Antibody, Anti-Native DNA, Anti-Double Stranded DNA, Crithidia Assay
Double stranded anti-DNA antibody
DSDNA
Clinical significance:
High titers of antibodies to double-stranded DNA (dsDNA) are associated with systemic lupus erythematosus (SLE). The titer may decrease with succesful therapy and increase in acute recurrence of the disease.
Doctoral Director(s:)
Hoi-Ying Elsie Yu PhD, DABCC    
Review Date: 12/12/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Monday-Friday, 1st shift
Performed stat? No
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