Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

JO-1 MYOSITIS PANEL

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2736         Geisinger Epic ID: 41284

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Specimen required:
One 0.5 mL aliquot from the SST AND two 3.0 mL aliquots from the plain red-top tubes.
Special notes:
Collect one (1) serum separator tube (SST) for tests performed at GMC Immunology AND two (2) non-serum separator (plain) tubes for additional tests sent to Quest Diagnostics.

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit one 0.5 mL aliquot from the SST and two 3.0 mL aliquots from the plain red-top tubes. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours; 2-8 C: 48 hours. Frozen: 6 months. The sendout testing to Quest is stable 14 days refrigerated.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Reference interval:
Negative.
Additional information:
The JO1 antibody testing is performed in the Immunopathology Laboratory at GMC Danville campus. Additional tests for myositis are sent to Quest Diagnostics.
CPT code(s):
86235 x3 83516 x5
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Antibody testing for JO1, PL-7, PL-12, Mi-2, Ku, EJ, OJ, SRP.
Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA)
Radioimmunopreciptation assay (RIPA)
Synonyms:
Myositis panel
JO1 with reflex myositis
JO1RM
Clinical significance:
A positive JO1 antibody can be used in conjunction with other laboratory tests and clinical findings to aid in the diagnosis of polymyositis and other related connective diseases.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Stacy Kenyon, PhD, DABCC
   
Review Date: 12/02/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Two days per week, 1st shift.
Performed stat? No

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Tuesday-Saturday    
Performed stat? No
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