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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
HPV GENOTYPES 16 AND 18, CERVICAL |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2495 Geisinger Epic ID: 39184 | |
SPECIMEN COLLECTION |
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Specimen type: |
ThinPrep®: 3 mL of residual (PreservCyt®) fluid (1.5 mL min) or SurePath®: 2 mL of residual SurePath® fluid (1 mL min). |
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Preferred collection container: |
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Specimen required: |
ThinPrep®: 3 mL of residual (PreservCyt®) fluid (1.5 mL min) or SurePath®: 2 mL of residual SurePath® fluid (1 mL min). |
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Special notes: |
The HPV Genotype assay is validated for liquid cytology specimens only. Both Cytyc ThinPrep® and TriPath SurePath® samples are acceptable. Collect the sample as usual according to the manufacturer's instructions. | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Room temperature. | |
Specimen stability: |
PreservCyt® fluid is stable 6 months at room temperature or refrigerated. SurePath® is stable 30 days at room temperature or 6 months refrigerated. Frozen: Unacceptable. | |
Rejection criteria: |
Received frozen. Cervical swabs in Digene® HC cervical sampler • SurePath™ vial without cervical brush/broom • Swabs • SurePath™ pellet • Samples treated with Acetic Acid • Vaginal sources | |
TEST DETAILS |
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CPT code(s): |
87625 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
HPV 16, HPV 18 | |
Methodology: |
Real-time Polymerase Chain Reaction (PCR) |
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Synonyms: |
HPV (human papilloma virus) genotypes 16 and 18 Quest test code 19865 HPVGEN
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Clinical significance: |
Persistent infection with high-risk HPV types increases a woman's risk for progression to dysplasia or cervical cancer. The rate of progression or degree of risk depends on the HPV type. Of all various high-risk types, HPV Types 16 and 18 cause more than 60-65% of cervical cancers. This test will identify the presence or absence of HPV Type 16 DNA and/or Type 18 DNA. Knowledge of the HPV genotype will help physicians diagnose the type of HPV infection and its risk of developing into dysplasia or cervical cancer. | |