Geisinger Medical Laboratories Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

UROVYSION ASSAY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB4105         Geisinger Epic ID: 37264

SPECIMEN COLLECTION
Specimen type:
Voided urine
Preferred collection container:
Specimen required:
33 mL of voided urine with 17 mL of Saccomanno preservative added (total volume 50mL) in labeled collection container.
Special notes:
Minimum 33 mL voided urine required. > 33 mL preferred.

SPECIMEN PROCESSING
Specimen processing instructions:
With Saccomanno preservative added may be transported room temperature within 12 hours of collection. 
Transport temperature:
Room temperature (with Saccomanno preservative added). If transport time exceeds 12 hours or temperature exceeds 25C, refrigerate specimen and send with ice packs.
Specimen stability:
72 hours from collection to processing.
Rejection criteria:
Inadequate patient identifiers on specimen, unlabeled specimen, discrepancy between patient specimen and requisition information, improper collection. Specimen received at room temperature without Saccomanno preservative added.

TEST DETAILS
Reference interval:
Abnormal: > or = 4 cells with gains of 2 or more chromosomes 3, 7, or 17 in the same cells or > or = 12 cells with homozygous 9p21 deletion
CPT code(s):
88120 (manual), 88121 (auto)
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Fluorescence In Situ Hybridization (FISH)
Synonyms:
UroVysion, UroVysion FISH, UroVysion assay, FISH for bladder cancer
Clinical significance:
The UroVysion TM assay is a FISH assay for the detection of urothelial carcinoma. The UroVysion TM probe set contains probes to the centromeres of chromosomes 3, 7, and 17. And a locus specific probe for 9p21 band.
Doctoral Director(s:)
Hong Yin MD    
Review Date: 12/23/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: FISH
Technical Lead: Michele Zelonis
Frequency: Monday-Friday
Performed STAT? No

Geisinger Wyoming Valley Medical Center

Performing laboratory: FISH
Technical Lead: Lisa DiPippa    
Frequency: Monday-Friday    
Performed STAT? No
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