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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
HU ANTIBODY SCREEN W/REFLEX TO TITER & WB, CSF |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1761 Geisinger Epic ID: 35857 | |
SPECIMEN COLLECTION |
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Specimen type: |
Cerebrospinal fluid (CSF) | |
Preferred collection container: |
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Specimen required: |
3 mL (minimum 1.5 mL) CSF | |
Patient preparation: |
Overnight fasting is preferred. | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: Unacceptable. Refrigerated: 1 week. Frozen: 6 months. | |
Rejection criteria: |
Room temperature specimen. | |
TEST DETAILS |
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Reference interval: |
Accompanies report. | |
CPT code(s): |
86255 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
HU antibody screen with reflex to titer and Western Blot, CSF. If Hu Antibody Screen, IFA, CSF is positive, Hu Antibody, WB, CSF will be performed at an additional charge (CPT code(s): 84181). If Hu Antibody, WB, CSF is positive, Hu Antibody Titer, CSF will be performed at an additional charge (CPT code(s): 86256). | |
Methodology: |
Indirect Immunofluorescent Antibody (IFA) Western Blot |
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Synonyms: |
NEURONAL NUCLEAR ANTIBODY (HU), CSF HUABSF
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Clinical significance: |
Paraneoplastic Syndrome involves non-metastatic systemic effects that accompany malignant disease. Antineuronal Nuclear Antibody (Anti-Hu) is found in 5-10% of patients with small cell carcinoma of the lung. Anti-Hu is associated with subacute syndrome of encephalomyeloradiculopathy, sensory neuropathy, and autoimmune neuropathy, predominantly affecting the gastrointestinal tract. | |