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Geisinger Medical Laboratories Test Catalog
ANTINUCLEAR ANTIBODY (ANA), IFA |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1768 Geisinger Epic ID: 41286 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 1 mL serum. | |
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | |
Specimen stability: |
Room temperature: 8 hours. Refrigerated 2-8°C: 4 days (96 hours). Frozen: 6 months. | |
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | |
TEST DETAILS |
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Reference interval: |
<1:80 | |
Additional information: |
This assay is intended for the Rheumatology Department for those patients who were ANA EIA negative. | |
CPT code(s): |
86039 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
ANA titer and pattern. | |
Methodology: |
Indirect Immunofluorescent Antibody (IFA) |
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Synonyms: |
ANA IFA, ANA pattern and titer, centromere, ANA titer Antinuclear AB titer and pattern ANAIFA
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Clinical significance: |
The presence of ANA antibodies in correlation with clinical findings and other laboratory tests can aid in the diagnosis of certain rheumatic diseases including systemic lupus erythematosus (SLE), Sjogren's syndrome, mixed connective tissue disease, scleroderma, drug-induced lupus, and rheumatoid arthritis. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC | |
| Review Date: | 12/13/2022 | |