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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
IRON SCREEN, INCLUDING TIBC |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2556 Geisinger Epic ID: 14952 | ||||||||||||
SPECIMEN COLLECTION |
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Specimen type: |
Plasma or serum |
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Preferred collection container: |
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Specimen required: |
1 mL of serum or plasma; minimum 0.2 mL | ||||||||||||
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow serum to clot. Centrifuge to separate serum or plasma within 2 hours of collection. | ||||||||||||
Transport temperature: |
Refrigerated (preferred) or room temperature. | ||||||||||||
Specimen stability: |
Room temperature: 4 days. Refrigerated: 7 days. | ||||||||||||
Rejection criteria: |
Hemolyzed specimens are not acceptable. | ||||||||||||
TEST DETAILS |
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Reference interval: |
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CPT code(s): |
83540, 83550 | ||||||||||||
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | |||||||||||||
Test includes: |
Iron, Iron Binding Capacity | ||||||||||||
Methodology: |
Spectrophotometric (Colorimetric) |
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Synonyms: |
IRON SCREEN TRANSFERRIN SATURATION, FESCRN
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Clinical significance: |
Serum iron quantification is useful in confirming the diagnosis of iron-deficiency anemia or hemochromatosis. The measurement of total iron binding in the same specimen may facilitate the clinician's ability to distinguish between low serum iron levels caused by iron deficiency from those related to inflammatory neoplastic disorders. The assay for iron measures the amount of iron which is bound to transferrin. The total iron binding capacity (TIBC) measures the amount of iron that would appear in blood if all the transferrin were saturated with iron. It is an indirect measurement of transferrin concentrations but expressed as an iron measurement. To obtain the percent saturation, the serum iron is divided by the TIBC which gives the actual amount of saturated tranferrin. The percentage saturation is low in iron deficiency anemia and high in iron storage diseases. | ||||||||||||
Doctoral Director(s:) |
Hoi-Ying Elsie Yu, PhD, DABCC Sheng-Ying (Margaret) Lo, PhD, DABCC |
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| Review Date: | 02/22/2023 | ||||||||||||