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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
INTRINSIC FACTOR BLOCKING ANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2544 Geisinger Epic ID: 15285 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum. | |
Preferred collection container: |
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Specimen required: |
1 mL aliquot serum; minimum 0.3 mL. | |
Patient preparation: |
Samples should not be collected from a patient who has received Vitamin B12 injection therapy within the last week. | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Centrifuge and transfer serum specimens to clean, plastic, screw-capped vial(s). | |
Transport temperature: |
Room temperature (preferred). Refrigerated or frozen specimen also acceptable. | |
Specimen stability: |
Room temperature: 7 days. Refrigerated: 7 days. Frozen: 28 days. | |
Rejection criteria: |
Stability limits exceeded. | |
TEST DETAILS |
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Reference interval: |
Negative. | |
CPT code(s): |
86340 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Detection of intrinsic factor blocking antibody. | |
Methodology: |
Immunoassay |
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Synonyms: |
Intrinsic factor antibody, INTFAC Quest test code 568
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Clinical significance: |
Intrinsic Factor, produced by cells lining the stomach, binds vitamin B12 (cyanocobalamin) to facilitate absorption of the vitamin. Blocking antibody impedes the action of Intrinsic Factor, as observed in approximately half of the patients who develop pernicious anemia. | |