Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

TSI (THYROID STIMULATING IMMUNOGLOBULIN)

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3161         Geisinger Epic ID: 17556

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Specimen required:
1 mL aliquot of serum; minimum 0.2 mL.

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge and transfer serum specimens to clean, plastic, screw-capped vial(s). Transport on refrigerant coolant. 
Transport temperature:
Refrigerated.
Specimen stability:
Refrigerated: 21 days (preferred). Frozen: 60 days.
Rejection criteria:
Room temperature specimens will be rejected. Grossly hemolyzed, iteric and lipemic specimens will be rejected.

TEST DETAILS
Reference interval:
< 140% of baseline.
Additional information:
Please note: A serum TSH level >25 uIU/mL can interfere with the TSI bioassay, and potentially give higher TSI results
CPT code(s):
84445
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Thyroid Stimulating Immunoglobulin
Methodology:
Immunoassay
Synonyms:
Thyroid Stimulating Immun, THSI
Quest test code 30551
Clinical significance:
Graves' disease is a classic form of hyperthyroid disease, affecting approximately 0.4% of the population in the United States. It is caused by IgG immunoglobulins, collectively known as thyroid stimulating immunoglobulins (TSI). Patients who are candidates for antithyroid drug therapy may not respond to this treatment when TSI levels are markedly elevated. The determination of TSI can also assist in predicting hyperthyroidism in neonates, due to placental transmission of the immunoglobulins from a mother with hyperthyroidism.

Performing Locations

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Monday-Saturday mornings    
Performed stat? No
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