Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

ADRENOCORTICOTROPIC HORMONE

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB1531         Geisinger Epic ID: 6418

SPECIMEN COLLECTION
Specimen type:
Plasma
Preferred collection container:
Alternate Collection Container:
Lavender-top (K2 EDTA) microcollection tube
Specimen required:
1 mL aliquot frozen plasma; minimum 0.5 mL. Please submit a separate frozen aliquot for this test. It may not be combined with any other test requiring a frozen aliquot.
Special notes:
Inpatients: Collect in iced EDTA tubes only and transport in ice bath to lab for processing (cup with water and a small amount of ice will work well). If off-site, separate plasma from cells and submit 1 mL aliquot frozen. Plasma levels of ACTH exhibit significant diurnal variation. Because of this, collection is recommended at approximately 9 a.m. If collecting specimen in microcollection tubes, collect 3 FULL lavender microcollection tubes.

SPECIMEN PROCESSING
Specimen processing instructions:
Centrifuge, remove plasma, and freeze immediately. Submit 1 mL aliquot of plasma. 
Transport temperature:
Frozen.
Specimen stability:
30 days at -20°C.
Rejection criteria:
Frozen EDTA plasma is the ONLY suitable specimen. Any other specimen will be rejected. Specimens will also be rejected for hemolysis, icteremia, and lipemia.

TEST DETAILS
Reference interval:
<46 pg/mL for a.m. draws.
CPT code(s):
82024
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Adrenocorticotropic hormone value.
Methodology:
Chemiluminescence Immunoassay
Synonyms:
Adrenocorticotropic hormone, ACTH, CORTICOTROPIN, ADRENAL CORTICOTROPIN, CORTROSYN
Clinical significance:
ACTH determinations are valuable in the differential diagnosis of adrenal insufficiency and hypersecretion. In primary adrenal insufficiency (Addison's disease), elevated levels of ACTH are typical, while low levels are the rule when adrenal insufficiency is secondary to pituitary dysfunction. ACTH may also be used to identify the cause of cortisol hypersecretion in Cushing's syndrome.
Doctoral Director(s:)
Hoi-Ying Elsie Yu PhD, DABCC    
Review Date: 12/02/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Karen Delp
Frequency: Twice weekly.
Performed stat? No
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