Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

ACTIN (SMOOTH MUSCLE) ANTIBODY (IGG)

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3062         Geisinger Epic ID: 34847

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.25 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and aliquot. 
Transport temperature:
Room temperature.
Specimen stability:
Room temperature: 14 days. Refrigerated: 14 days. Frozen: 30 days.
Rejection criteria:
Gross hemolysis • Lipemia • Microbially contaminated serum • Specimens containing heavy, visible particulate

TEST DETAILS
CPT code(s):
86015
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms:
Quest code 15043, Anti-Smooth Muscle Ab IgG,ASMA IgG,F-Actin Antibody,Smooth Muscle Antibody IgG
Clinical significance:
Actin is the major antigen to which smooth muscle antibodies react in autoimmune hepatitis. F-Actin IGG antibodies are found in 52-85% of patients with Autoimmune Hepatitis (AIH) or chronic active hepatitis and in 22% of patients with Primary Biliary Cirrhosis (PBC). Anti-Actin antibodies have been reported in 3-18% of sera from normal healthy controls.

Performing Locations

Quest Diagnostics

Technical Lead: Michael Weaver    
Frequency: Set up: Tuesday-Saturday. Report available: Next day.    
Performed STAT? No
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