Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

SMOOTH MUSCLE ANTIBODY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3062         Geisinger Epic ID: 34847

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Interpretation guide:
Negative: <20 units; Weak positive: 20-30 units; Moderate to strong positive: = 30 units.
CPT code(s):
83516
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Antibody detection to Actin IGG antibody
Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms:
ASMA, Anti-Smooth Muscle Antibody
Anti-SM Muscle AB
F-Actin, Actin IgG
ACTIN
Clinical significance:
The presence of antibodies to anti-mitochondrial, gp210 and sp100 when used in conjunction with clinical findings and other laboratory tests can aid in the diagnosis of primary biliary cirrhosis.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Stacy Kenyon, PhD, DABCC
   
Review Date: 12/03/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Two days per week, 1st shift.
Performed stat? No
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