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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
5-HYDROXYINDOLEACETIC ACID W/CREATININE, 24 HR UR |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB1491 Geisinger Epic ID: 15006 | |
SPECIMEN COLLECTION |
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Specimen type: |
24-hour urine. | |
Preferred collection container: |
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Specimen required: |
10 mL aliquot (minimum 5 mL) of 24-hour urine preserved with 25 mL 6N HCl. | |
Special notes: |
Preserve 24-hour urine with 25 mL 6N HCl to maintain a pH below 3. Mix well. Estimate total collection volume from 24-hour urine container. Remove required aliquot. Record total volume on both aliquot tube and request slip (if applicable). | |
Patient preparation: |
Patient should avoid food high in indoles: avocado, banana, tomato, plum, walnut, pineapple, and eggplant. | |
| SPECIMEN PROCESSING |
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Transport temperature: |
Refrigerated. | |
Specimen stability: |
Room temperature: 7 days. Refrigerated: 30 days. Frozen: 30 days. | |
Rejection criteria: |
Preserved urine received refrigerated with a pH >3. | |
TEST DETAILS |
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CPT code(s): |
82570, 83497 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
5-HIAA and creatinine, 24-hour urine | |
Methodology: |
High Performance Liquid Chromatography (HPLC) Electrochemical detection |
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Synonyms: |
5-hydroxyindoleacetic acid, HIAA24 Quest test code 39625
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Clinical significance: |
5-HIAA is the end product of serotonin (5-hydroxytryptophan) and tyrptophan metabolism. Patients with carcinoid tumors of the midgut, e.g., ileum, produce high concentrations of 5-HIAA. Patients with carcinoid tumors of the foregut and hindgut may produce little or no 5-HIAA or do so intermittently. | |