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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
CREATININE CLEARANCE |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB2091 Geisinger Epic ID: 6581 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum OR plasma AND 24-hour urine | |
Preferred collection container: |
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Specimen required: |
1 mL of serum or plasma, minimum 0.2 mL; AND 10 mL aliquot of 24-hour urine, minimum 2 mL | |
Special notes: |
Collect urine in 24-hour urine collection container, either with 6N HCl added or with no preservative added. Mix well. Estimate total collection volume from 24-hour urine container. Remove required aliquot. Record total volume on both aliquot tube and request slip (if applicable). Lithium heparin plasma is acceptable from in-house collection. Provide patient height and weight on lab request (centimeters and kilograms). Serum or plasma should be collected within 24 hours of collection of the 24-hour urine specimen. |
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| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow serum to clot. Centrifuge to separate serum or plasma within 2 hours of collection. | |
Transport temperature: |
Refrigerated. | |
Specimen stability: |
See individual member listing. | |
Rejection criteria: |
A complete 24-hour urine collection is required. Other specimens will be rejected. | |
TEST DETAILS |
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Reference interval: |
Creatinine clearance: Male 85-125 mL/min; female: 75-115 mL/min Urine creatinine: Male: 1-2 gm/24 hours; female 0.8-1.8 gm/24 hours Serum creatinine: 0.7-1.5 mg/dL. Age and sex dependent. |
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CPT code(s): |
82575 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Creatinine clearance creatinine - 24-hour urine creatinine - serum 24-hour total volume | |
Methodology: |
Enzymatic |
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Synonyms: |
CREATININE CLEARANCE, URINE, CLRB
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Clinical significance: |
Creatinine clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant when there is massive injury to muscle. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu, PhD, DABCC Sheng-Ying (Margaret) Lo, PhD, DABCC |
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| Review Date: | 12/14/2022 | |