Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

CREATININE CLEARANCE

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2091         Geisinger Epic ID: 6581

SPECIMEN COLLECTION
Specimen type:
Serum OR plasma AND 24-hour urine
Preferred collection container:
Specimen required:
1 mL of serum or plasma, minimum 0.2 mL; AND 10 mL aliquot of 24-hour urine, minimum 2 mL
Special notes:
Collect urine in 24-hour urine collection container, either with 6N HCl added or with no preservative added. Mix well. Estimate total collection volume from 24-hour urine container. Remove required aliquot. Record total volume on both aliquot tube and request slip (if applicable).

Lithium heparin plasma is acceptable from in-house collection.

Provide patient height and weight on lab request (centimeters and kilograms). Serum or plasma should be collected within 24 hours of collection of the 24-hour urine specimen.

SPECIMEN PROCESSING
Specimen processing instructions:
Allow serum to clot. Centrifuge to separate serum or plasma. 
Transport temperature:
Refrigerated.
Specimen stability:
See individual member listing.
Rejection criteria:
A complete 24-hour urine collection is required. Other specimens will be rejected.

TEST DETAILS
Reference interval:
Creatinine clearance: Male 85-125 mL/min; female: 75-115 mL/min
Urine creatinine: Male: 1-2 gm/24 hours; female 0.8-1.8 gm/24 hours
Serum creatinine: 0.7-1.5 mg/dL. Age and sex dependent.
CPT code(s):
82575
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
Creatinine clearance creatinine - 24-hour urine creatinine - serum 24-hour total volume
Methodology:
Spectrophotometric (Colorimetric)
Synonyms:
CREATININE CLEARANCE, URINE, CLRB
Clinical significance:
Creatinine clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant when there is massive injury to muscle.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Sheng-Ying (Margaret) Lo, PhD, DABCC    
Review Date: 12/24/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Automated Chemistry
Technical Lead: Jared Shepard
Frequency: Daily, Monday - Sunday
Performed stat? No

Geisinger Bloomsburg Hospital

Performing laboratory: Chemistry
Technical Lead: Robyn Stokes  
Frequency: Daily    
Performed stat? Yes

Geisinger Community Medical Center

Performing laboratory: Chemistry
Technical Lead: Ann Mack, Deborah Dempsey  
Frequency: Daily, all shifts    
Performed stat? Yes

Geisinger Lewistown Hospital

Performing laboratory: Chemistry
Technical Lead: Melissa Forsythe  
Frequency: All shifts    
Performed stat? Yes
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