Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

CMV IGM ANTIBODY

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB2171         Geisinger Epic ID: 7421

SPECIMEN COLLECTION
Specimen type:
 Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL
Patient preparation:
 None.
SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
 Refrigerated (preferred). Room temperature (stable 8 hours) or frozen specimen also acceptable.
Specimen stability:
 Room temperature: 8 hours. 2-8°C: 4 days. Frozen: 6 months
Rejection criteria:
 Specimen stability exceeded; specimen grossly hemolyzed.
TEST DETAILS
Interpretation guide:
Result
Interpretation
Negative Absence of detectable CMV IgM antibodies. A negative result, however, does not always rule out acute hCMV infection. The IgM response may not be detectable in the very early stage of infection or if the patient is immunocompromised. If clinical exposure to hCMV is suspected despite a negative finding, a second sample should be collected and tested no less than one to two weeks later.
Equivocal Suggest a second sample be collected and tested one to two weeks later.
Positive Presence of detectable CMV IgM antibodies. A positive result is generally indicative of acute infection, reactivation, or persistent IgM production.
CPT code(s):
 86645
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
 Qualitative determination of IgM antibodies to cytomegalovirus.
Methodology:
Chemiluminescence
Synonyms:
CMV IgM, Cytomegalovirus IgM, CMVM, TORCH
CMV IGM AB, Cytomegalovirus antibody IgM
Clinical significance:
Cytomegalovirus (CMV) exposure occurs throughout life, and by adulthood 50-90% of the population is seropositive for CMV antibodies. A single positive CMV IgG result is useful in distinguishing subjects who have been exposed to the virus from those who have not and by itself is indicative of a prior infection. Testing for CMV IgM antibodies is recommended to support a diagnosis of a current infection.
Doctoral Director(s:)
Hoi-Ying Elsie Yu PhD, DABCC    
Review Date: 12/13/2022

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Five days per week, 1st shift.
Performed STAT? No
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