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Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog
TISSUE TRANSGLUTAMINASE IGA ANTIBODY |
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ORDERING INFORMATION: |
Geisinger Epic Procedure Code: LAB3166 Geisinger Epic ID: 18314 | |
SPECIMEN COLLECTION |
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Specimen type: |
Serum | |
Preferred collection container: |
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Alternate Collection Container: |
6 mL red-top (plain, non-serum separator) tube
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Specimen required: |
0.5 mL serum; minimum 0.2 mL | |
| SPECIMEN PROCESSING |
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Specimen processing instructions: |
Allow to clot. Centrifuge and submit 0.5 mL serum. | |
Transport temperature: |
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable. | |
Specimen stability: |
Room temperature: 8 hours. Refrigerated (2-8°C): 96 hours. Frozen: 6 months. | |
Rejection criteria: |
Specimen stability exceeded; specimen grossly hemolyzed. | |
TEST DETAILS |
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Reference interval: |
Negative <7 U/mL | |
Interpretation guide: |
Negative <7 U/mL Equivocal 7-10 U/mL Positive >10 U/mL |
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CPT code(s): |
86364 | |
| Note: The billing party has sole responsibility for CPT coding. Any questions regarding coding should be directed to the payer being billed. The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only. | ||
Test includes: |
Antibody detection to TTG IgA. | |
Methodology: |
Enzyme Immunoassay (EIA) |
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Synonyms: |
TTG, Tissue Transglutaminase Antibody IgA, Celiac T Transglutaminase Ab IgA, celiac disease
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Clinical significance: |
Antibodies to tissue transglutaminase (TTG) can be used to aid in the diagnosis of certain gluten-sensitive enteropathies such as celiac disease and dermatitis herpetiformis. This assay can also be used to check for adherence to a gluten-free diet in patients already diagnosed with celiac disease. | |
Doctoral Director(s:) |
Hoi-Ying Elsie Yu PhD, DABCC | |
| Review Date: | 12/13/2022 | |