Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

PLATELET FUNCTION ASSAY PANEL

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3490         Geisinger Epic ID: 119767

SPECIMEN COLLECTION
Specimen type:
Whole blood
Preferred collection container:
Other size blue-top (3.2% sodium citrate) tubes (e.g., 1.8 mL, 4.5 mL)
Alternate Collection Container:
Lavender-top (K2 EDTA) microcollection tube
Specimen required:
2.7 mL whole blood.
Special notes:
Collect BOTH blue-top and lavender-top tube. BOTH are required. A lavender-top (K2 EDTA) microcollection tube may also be used.
Specimen must be collected with a needle diameter no smaller than a 21 gauge. Test may only be collected and performed at testing laboratories (see below). Send blood specimen to lab as soon as possible after collection. Do not transport specimens via pneumatic tube. Test offered at limited performing laboratories (see below).
Patient preparation:
Patient's hematocrit must be greater than 35%. Patient's platelet count must be greater than 150,000/uL. Patient should not be on any medication known to affect platelet function.

SPECIMEN PROCESSING
Specimen processing instructions:
Do not centrifuge, refrigerate or freeze specimen. Do not ship specimen through the pneumatic tube system. 
Transport temperature:
Room temperature.
Specimen stability:
Specimen is stable for up to four hours.
Rejection criteria:
Clotted specimen. Hematocrit < 30%. Platelet count < 50,000/┬ÁL. Overfilled or underfilled tubes. Stability limits exceeded.

TEST DETAILS
Reference interval:
89-193 seconds Collagen/EPI
64-120 seconds Collagen/ADP.
Interpretation guide:
Prolongation (EPI >193 sec and ADP >120 sec) indicates decreased platelet function, low HCT, or low platelets (PLT). Aspirin-like drugs prolong EPI cartridge only. Von Willebrand disease, intrinsic platelet dysfunction, and non-aspirin drugs prolong EPI and ADP. Shortened times (EPI<89 sec & APD <64 sec) associated with increased PLT number or function. The PFA-100 is insensitive to thienopyridine drugs (clopidogrel).
CPT code(s):
85576
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
PFA100(EPI/COLL), HCT, PLT, PFA100 (ADP/COLL), if indicated.
Methodology:
Measures platelet adhesion and aggregation in whole blood using a high-shear testing system
Synonyms:
PFA, PFA 100, PLATELET FUNCTION SCREEN
PFASCR
Clinical significance:
Platelet function screen test is used to screen patients suspected of having a platelet dysfunction that may be caused by intrinsic platelet defects, von Willebrand disease, or exposure to platelet inhibiting agents.
Doctoral Director(s:)
Michelle Grant DO    
Review Date: 04/29/2019

Performing Locations

Geisinger Medical Center

Performing laboratory: Coagulation
Technical Lead: Margaret Knowles-Tuchman
Frequency: Daily all shifts
Performed stat? Yes

Geisinger Wyoming Valley Medical Center

Performing laboratory: ATL+
Technical Lead: Julia Bell    
Frequency: Daily, all shifts    
Performed stat? No

Geisinger Community Medical Center

Performing laboratory: Hematology
Technical Lead: Renee Bordo, Robert Furcon  
Frequency: Daily, all shifts    
Performed stat? Yes

Geisinger Lewistown Hospital

Performing laboratory: Hematology
Technical Lead: Lisa Sheaffer  
Frequency: All shifts    
Performed stat? Yes
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