Geisinger Medical Laboratories/Geisinger Proven Diagnostics Test Catalog

Order Display Name: Geisinger Epic Procedure Code Or ID CPT Code:  

SSA/RO AND SSB/LA ANTIBODIES

ORDERING INFORMATION:
Geisinger Epic Procedure Code: LAB3083         Geisinger Epic ID: 15195

SPECIMEN COLLECTION
Specimen type:
Serum
Preferred collection container:
Alternate Collection Container:
6 mL red-top (plain, non-serum separator) tube
Specimen required:
0.5 mL serum; minimum 0.2 mL

SPECIMEN PROCESSING
Specimen processing instructions:
Allow to clot. Centrifuge and submit 0.5 mL serum. 
Transport temperature:
Refrigerated (preferred). Room temperature (stable 8 hours) and frozen specimens also acceptable.
Specimen stability:
Room temperature: 8 hours. 2-8°C: 48 hours. Frozen: 6 months.
Rejection criteria:
Specimen stability exceeded; specimen grossly hemolyzed.

TEST DETAILS
Interpretation guide:
Normal range/negative < 20
Weak Positive 20-39
Moderate Positive 40-80
Strong Positive > 80
CPT code(s):
86235 x 2
Note: The billing party has sole responsibility for CPT coding.  Any questions regarding coding should be directed to the payer being billed.  The CPT codes provided by GML are based on AMA guidelines and are for informational purposes only.
Test includes:
SSA Antibody, SSB Antibody
Methodology:
Enzyme-Linked Immunosorbent Assay (ELISA)
Synonyms:
Sjogren syndrome, Sjogren's syndrome, SSASSB
ENA (Extractable nuclear antigen), RO and La antibodies
ANTI-ENA, ANTI-RO, ANTI-LA
SSA/SSB Antibodies
Clinical significance:
SS-A and SS-B antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of systemic lupus erythematosus (SLE) and related connective tissue diseases, such as Sjogren's syndrome.
Doctoral Director(s:)
Hoi-Ying Elsie Yu, PhD, DABCC
Stacy Kenyon, PhD, DABCC
   
Review Date: 12/02/2020

Performing Locations

Geisinger Medical Center

Performing laboratory: Immunology
Technical Lead: Kathy Hurst
Frequency: Two days per week, 1st shift.
Performed stat? No
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